Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 10/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1873310 | 1.00 | BRAF (0.47) | BRAFKLKB1FLT3MASP2NAMPT | |
| SCHEMBL1861627 | 0.91 | BRAF (0.45) | BRAFKLKB1FLT3MASP2NAMPT | |
| SCHEMBL1861630 | 0.91 | BRAF (0.45) | BRAFKLKB1FLT3MASP2NAMPT | |
| SCHEMBL1868561 | 0.89 | BRAF (0.43) | BRAFKLKB1FLT3MASP2 | |
| SCHEMBL1868558 | 0.89 | BRAF (0.43) | BRAFKLKB1FLT3MASP2 | |
| SCHEMBL1865734 | 0.89 | KLKB1 (0.45) | BRAFKLKB1FLT3MASP2NAMPT | |
| SCHEMBL1865731 | 0.89 | KLKB1 (0.45) | BRAFKLKB1FLT3MASP2NAMPT | |
| SCHEMBL1863382 | 0.88 | BRAF (0.47) | BRAFKLKB1FLT3MASP2NAMPT | |
| SCHEMBL1863379 | 0.88 | BRAF (0.47) | BRAFKLKB1FLT3MASP2NAMPT | |
| SCHEMBL1870114 | 0.88 | BRAF (0.47) | BRAFKLKB1FLT3MASP2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |