SCHEMBL1865773

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1858111	0.84	RAB9A (0.78)	RAB9ATP53L3MBTL1MAPTSMN1; SMN2
	SCHEMBL1861604	0.81	HDAC1 (0.61)	RAB9ATP53L3MBTL1MAPTSMN1; SMN2
	SCHEMBL1861725	0.80	RAB9A (0.62)	RAB9ATP53L3MBTL1TSHRMAPT
	SCHEMBL1867882	0.78	GAA (0.64)	RAB9ATP53L3MBTL1HPGDTSHR
	SCHEMBL1865862	0.78	GAA (0.54)	RAB9ATP53HPGDTSHRMAPT
	SCHEMBL27572930	0.77	F2 (0.52)	RAB9ATP53HPGDMAPTSMN1; SMN2
	SCHEMBL4739925	0.77	RAB9A (0.73)	RAB9ATP53L3MBTL1MAPTSMN1; SMN2
	SCHEMBL15988680	0.77	HPGD (0.77)	RAB9AL3MBTL1HPGDTSHRMAPT
	SCHEMBL8345583	0.76	RAB9A (0.62)	RAB9ATP53L3MBTL1TSHRMAPT
	SCHEMBL5903862	0.75	RAB9A (0.57)	RAB9ATP53L3MBTL1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.