Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12745739 | 1.00 | MAPK1 (0.31) | MAPK1NPSR1ALDH1A1TSHR | |
| SCHEMBL12826667 | 0.86 | MAPK1 (0.31) | MAPK1NPSR1 | |
| SCHEMBL18658551 | 0.84 | MAPK1 (0.30) | MAPK1NPSR1 | |
| SCHEMBL18658561 | 0.84 | MAPK1 (0.30) | MAPK1NPSR1 | |
| SCHEMBL3741969 | 0.83 | MAPK1 (0.33) | MAPK1NPSR1 | |
| SCHEMBL3741967 | 0.83 | MAPK1 (0.33) | MAPK1NPSR1 | |
| SCHEMBL19459747 | 0.81 | — | — | |
| SCHEMBL18658547 | 0.81 | MAPK1 (0.34) | MAPK1NPSR1ALDH1A1 | |
| SCHEMBL9305518 | 0.81 | MAPK1 (0.34) | MAPK1NPSR1ALDH1A1 | |
| SCHEMBL17861866 | 0.81 | LMNA (0.33) | MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2837629-B1 | METHOD FOR SYNTHESIZING SAPROPTERIN DIHYDROCHLORIDE | ASYMCHEM LABORATORIES (TIANJIN) CO LTD (CN) | 2017-03-22 | — | — | EP | disclosed |