Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18658547 | 1.00 | MAPK1 (0.34) | MAPK1NPSR1SUCNR1KDM4EALDH1A1 | |
| SCHEMBL3741967 | 0.82 | MAPK1 (0.33) | MAPK1NPSR1 | |
| SCHEMBL3741969 | 0.82 | MAPK1 (0.33) | MAPK1NPSR1 | |
| SCHEMBL12826667 | 0.81 | MAPK1 (0.31) | MAPK1NPSR1 | |
| SCHEMBL12745739 | 0.81 | MAPK1 (0.31) | MAPK1NPSR1ALDH1A1 | |
| SCHEMBL18658564 | 0.81 | MAPK1 (0.31) | MAPK1NPSR1ALDH1A1 | |
| SCHEMBL8999544 | 0.81 | MAPK1 (0.35) | MAPK1NPSR1SUCNR1KDM4EALDH1A1 | |
| SCHEMBL18658561 | 0.80 | MAPK1 (0.30) | MAPK1NPSR1 | |
| SCHEMBL18658551 | 0.80 | MAPK1 (0.30) | MAPK1NPSR1 | |
| SCHEMBL1595065 | 0.79 | SUCNR1 (0.45) | MAPK1NPSR1SUCNR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328638-A | Increasing spontaneous polarization | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0361272-A1 | Optically active esters of 5-ethyl and 5-vinyl 1,3-dioxolane-carboxylic acid, their use as dopants in liquid-crystal mixtures, and liquid-crystal mixtures containing these esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-04 | — | — | EP | disclosed |