Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18659989 | 0.90 | AKT1 (0.31) | AKT1PSMB5LMNA | |
| SCHEMBL23095657 | 0.89 | LMNA (0.31) | LMNA | |
| SCHEMBL20149199 | 0.87 | AKT1 (0.32) | AKT1POLBHSD17B10HPGDHTT | |
| SCHEMBL24533285 | 0.86 | AKT1 (0.33) | AKT1POLBHSD17B10HPGDHTT | |
| SCHEMBL19696373 | 0.86 | GSK3A (0.34) | AKT1POLBHSD17B10HPGDHTT | |
| SCHEMBL20805909 | 0.86 | KAT2A (0.33) | AKT1POLBHSD17B10HPGDHTT | |
| SCHEMBL18557382 | 0.86 | AKT1 (0.34) | AKT1POLBHSD17B10HPGDHTT | |
| SCHEMBL26521168 | 0.86 | SMN1; SMN2 (0.36) | AKT1POLBHSD17B10HPGDHTT | |
| SCHEMBL18494046 | 0.84 | LMNA (0.36) | AKT1POLBHSD17B10HPGDHTT | |
| SCHEMBL26034088 | 0.84 | CNR1 (0.38) | HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564674-A1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | Ventana Medical Systems, Inc. (US) | 2019-11-06 | — | — | EP | disclosed |
| EP-3276349-B1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MED SYST INC (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-3276349-A1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | Ventana Medical Systems, Inc. (US) | 2018-01-31 | — | — | EP | disclosed |
| EP-3029461-B1 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | VENTANA MED SYST INC (US) | 2017-12-20 | — | — | EP | disclosed |
| EP-3144675-A1 | ENZYMES CONJUGATED TO ANTIBODIES VIA A PEG HETEROBIFUCTIONAL LINKER | Ventana Medical Systems, Inc. (US) | 2017-03-22 | — | — | EP | disclosed |