Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22045070 | 0.93 | HPGD (0.38) | SMN1; SMN2HPGDHTTMGLLLMNA | |
| SCHEMBL26521168 | 0.90 | SMN1; SMN2 (0.36) | AKT1HSD17B10POLBSMN1; SMN2HPGD | |
| SCHEMBL18557382 | 0.90 | AKT1 (0.34) | AKT1HSD17B10POLBSMN1; SMN2HPGD | |
| SCHEMBL18494046 | 0.88 | LMNA (0.36) | AKT1HSD17B10POLBSMN1; SMN2HPGD | |
| SCHEMBL19696373 | 0.88 | GSK3A (0.34) | AKT1HSD17B10POLBSMN1; SMN2HPGD | |
| SCHEMBL24048990 | 0.87 | LMNA (0.33) | AKT1HSD17B10POLBSMN1; SMN2HPGD | |
| SCHEMBL18744100 | 0.87 | DUT (0.32) | AKT1HSD17B10POLBSMN1; SMN2HPGD | |
| SCHEMBL18639283 | 0.86 | AKT1 (0.34) | AKT1HSD17B10POLBSMN1; SMN2HPGD | |
| SCHEMBL18659926 | 0.86 | AKT1 (0.31) | AKT1HSD17B10POLBSMN1; SMN2HPGD | |
| SCHEMBL19882361 | 0.86 | AKT1 (0.32) | AKT1HSD17B10POLBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022130046-A1 | N-1 BRANCHED IMIDAZOQUINOLINES, CONJUGATES THEREOF, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-06-23 | — | — | WO | disclosed |