Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AOC1 | P19801 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30239656 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HTTRAB9AGAAMAPT | |
| SCHEMBL18232337 | 0.85 | ALDH1A1 (0.49) | ALDH1A1HTTRAB9AGAAMAPT | |
| SCHEMBL27755590 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTRAB9AGAAMAPT | |
| SCHEMBL28801025 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTRAB9AGAAMAPT | |
| SCHEMBL9469139 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTRAB9AGAAMAPT | |
| SCHEMBL10283705 | 0.81 | KDM4C (0.47) | ALDH1A1HTTRAB9AGAAMAPT | |
| SCHEMBL23852951 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTRAB9AGAAMAPT | |
| SCHEMBL2337025 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTRAB9AGAAMAPT | |
| SCHEMBL16657359 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTRAB9AGAAMAPT | |
| SCHEMBL9426306 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HTTRAB9AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552811-B2 | Immunosuppressant, and preparation method therefor and use thereof | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2026-02-17 | — | — | US | disclosed |
| US-12473282-B2 | Biphenyl fluorine double bond derivative, preparation method therefor, and pharmaceutical application thereof | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2025-11-18 | — | — | US | disclosed |
| CN-115605475-B | Immunosuppressant, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-118994208-B | Preparation method of biphenyl derivatives | 江苏豪森药业集团有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-118994208-A | Preparation method of biphenyl derivatives | 江苏豪森药业集团有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20240376076-A1 | INHIBITORS TARGETING UBIQUITIN SPECIFIC PROTEASE 7 (USP7) | DANA-FARBER CANCER INSTITUTE, INC. | 2024-11-14 | — | — | US | disclosed |
| CN-118401507-A | Inhibitors targeting ubiquitin-specific protease 7 (USP 7) | 丹娜法伯癌症研究院 | 2024-07-26 | — | — | CN | disclosed |
| CN-114502556-B | Biphenyl fluoro double bond derivative, preparation method thereof and application thereof in pharmacy | 上海和誉生物医药科技有限公司 | 2023-07-28 | — | — | CN | disclosed |
| US-20230234970-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| US-20230234970-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| WO-2003011864-A1 | DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2a RECEPTOR AND THEIR USE AS MEDICAMENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-02-13 | — | — | WO | disclosed |
| WO-2003011864-A1 | DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2a RECEPTOR AND THEIR USE AS MEDICAMENTS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-02-13 | — | — | WO | disclosed |
| US-5723468-A | COGNITION ACTIVATORS FOR MEMOY LOSS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-03 | — | — | US | disclosed |
| US-5571819-A | Imidazopyridines as muscarinic agents | WYETH | 1996-11-05 | — | — | US | disclosed |
| US-5371086-A | Circulatory disorders side effect reduction | THE GREEN CROSS CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5262415-A | FOR TREATING DISEASES OF THE CIRCULATORY SYSTEM | THE GREEN CROSS CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0503627-A1 | Aminopyridine compounds | THE GREEN CROSS CORPORATION (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4654350-A | Gaba-agonistic imidazo(4,5-c)pyridines useful as pharmaceuticals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-03-31 | — | — | US | disclosed |
| EP-0082369-B1 | IMIDAZO (4,5-C) PYRIDINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | MERCK PATENT GmbH (DE) | 1986-04-09 | — | — | EP | disclosed |
| EP-0082369-A1 | Imidazo (4,5-c) pyridines, pharmaceutical compositions containing them and process for their preparation | MERCK PATENT GmbH (DE) | 1983-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552811-B2 | Immunosuppressant, and preparation method therefor and use thereof | CD274, PDCD1, PDCD1LG2 | ALDH1A1 341/4885HTT 4192/4885RAB9A 2060/4885 |
| US-12473282-B2 | Biphenyl fluorine double bond derivative, preparation method therefor, and pharmaceutical application thereof | PDCD1, CD274, PDCD1LG2 | ALDH1A1 171/4885HTT 3776/4885RAB9A 2254/4885 |
| US-20230234970-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CD274, PDCD1, PDCD1LG2 | ALDH1A1 106/4885HTT 3993/4885RAB9A 1896/4885 |
| US-20240376076-A1 | INHIBITORS TARGETING UBIQUITIN SPECIFIC PROTEASE 7 (USP7) | USP7, USP47, USP2 | ALDH1A1 2692/4885HTT 1016/4885RAB9A 1457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.