Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469139 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL30239656 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL27755590 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL186601 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL16657372 | 0.79 | ALDH1A1 (0.82) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL28212317 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL23852951 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL16657375 | 0.77 | ALDH1A1 (0.70) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL16657359 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HTTRAB9AMEN1KMT2A | |
| SCHEMBL28570276 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HTTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102884063-A | Substituted aza-bicyclic imidazole derivatives useful as TRPM8 receptor modulators | JANSSEN PHARMACEUTICA NV | 2013-01-16 | — | — | CN | disclosed |