Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18663182 | 0.85 | IGF1R (0.30) | IGF1RALOX15 | |
| Hydrochloric Acid SCHEMBL18663197 | 0.81 | IGF1R (0.30) | IGF1RALOX15 | |
| Hydrochloric Acid SCHEMBL18663180 | 0.75 | — | — | |
| Bromide SCHEMBL18663127 | 0.73 | — | — | |
| Iodide SCHEMBL18663244 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL18663236 | 0.73 | IGF1R (0.30) | IGF1RALOX15 | |
| SCHEMBL18663204 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL18663134 | 0.70 | — | — | |
| SCHEMBL18663186 | 0.70 | — | — | |
| SCHEMBL18663181 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932423-B2 | Hydrogenation of annulated cyclopentadienyl metal complexes and metallocene catalysts comprising such | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170088643-A1 | HYDROGENATION OF ANNULATED CYCLOPENTADIENYL METAL COMPLEXES AND METALLOCENE CATALYSTS COMPRISING SUCH | UNIVATION TECHNOLOGIES, LLC | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088643-A1 | HYDROGENATION OF ANNULATED CYCLOPENTADIENYL METAL COMPLEXES AND METALLOCENE CATALYSTS COMPRISING SUCH | HMOX1, HHAT, HIRIP3 | IGF1R 3383/4885ALOX15 755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.