Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.65 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PER2 | O15055 | 3/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18664138 | 1.00 | PIK3CD (0.65) | PIK3CDDPP4CYP3A4TSHRTDP1 | |
| SCHEMBL18664137 | 1.00 | PIK3CD (0.65) | PIK3CDDPP4CYP3A4TSHRTDP1 | |
| SCHEMBL6545587 | 0.87 | PIK3CD (0.54) | PIK3CDDPP4CYP3A4TSHRTDP1 | |
| SCHEMBL22348923 | 0.85 | DPP4 (0.47) | PIK3CDDPP4CYP3A4TSHRTDP1 | |
| SCHEMBL22409043 | 0.80 | PIK3CD (0.48) | PIK3CDDPP4POLBPARP1 | |
| SCHEMBL28707173 | 0.80 | PIK3CD (0.48) | PIK3CDDPP4POLBPARP1 | |
| SCHEMBL24256488 | 0.78 | PIK3CD (0.67) | PIK3CDPOLBPER2CRY2 | |
| SCHEMBL19701910 | 0.78 | PIK3CD (1.00) | PIK3CDPOLBPER2CRY2 | |
| SCHEMBL16190279 | 0.78 | — | — | |
| SCHEMBL9255336 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017046606-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2017-03-23 | — | — | WO | disclosed |