Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.54 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18664136 | 0.87 | PIK3CD (0.65) | PIK3CDDPP4CYP3A4TSHRTDP1 | |
| SCHEMBL18664137 | 0.87 | PIK3CD (0.65) | PIK3CDDPP4CYP3A4TSHRTDP1 | |
| SCHEMBL18664138 | 0.87 | PIK3CD (0.65) | PIK3CDDPP4CYP3A4TSHRTDP1 | |
| SCHEMBL5638720 | 0.87 | DPP4 (0.41) | PIK3CDDPP4CYP3A4TSHRTDP1 | |
| SCHEMBL1527371 | 0.80 | CYP3A4 (0.39) | DPP4CYP3A4TSHRTDP1MAPT | |
| SCHEMBL4704959 | 0.80 | CYP3A4 (0.39) | DPP4CYP3A4TSHRTDP1MAPT | |
| SCHEMBL1527372 | 0.80 | CYP3A4 (0.39) | DPP4CYP3A4TSHRTDP1MAPT | |
| SCHEMBL7804695 | 0.79 | L3MBTL1 (0.39) | DPP4CYP3A4TSHRTDP1MAPT | |
| Hydrochloric Acid SCHEMBL15123967 | 0.79 | CYP3A4 (0.38) | DPP4CYP3A4TSHRTDP1MAPT | |
| Hydrochloric Acid SCHEMBL15123970 | 0.79 | CYP3A4 (0.38) | DPP4CYP3A4TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377542-A1 | HIV PROTEASE INHIBITORS BASED ON AMINO ACID DERIVATIVES | Pharmacor Inc. (CA) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002064551-A1 | HIV PROTEASE INHIBITORS BASED ON AMINO ACID DERIVATIVES | PHARMACOR INC. (CA) | 2002-08-22 | — | — | WO | disclosed |