SCHEMBL1866485

SCHEMBL1866485

CCCCCCCCC=CCCCCCCCCNC(=O)C(CN)NC(=O)CCCCCCCC=CCCCCCCCC

nearest known ligand 0.64

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SLC6A5 Q9Y345 3/20 0.64
▸ EPHX2 P34913 9/20 0.62
▸ LPAR3 Q9UBY5 5/20 0.56
▸ LPAR1 Q92633 2/20 0.55
▸ CNR1 P21554 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1866483 1.00 SLC6A5 (0.64) SLC6A5EPHX2LPAR3LPAR1CNR1
SCHEMBL12148896 1.00 SLC6A5 (0.64) SLC6A5EPHX2LPAR3LPAR1CNR1
SCHEMBL12087758 1.00 SLC6A5 (0.64) SLC6A5EPHX2LPAR3LPAR1CNR1
SCHEMBL16552975 0.96 CNR1 (0.60) SLC6A5EPHX2CNR1
SCHEMBL12667224 0.96 CNR1 (0.60) SLC6A5EPHX2CNR1
SCHEMBL16553079 0.96 CNR1 (0.60) SLC6A5EPHX2CNR1
SCHEMBL12667229 0.96 CNR1 (0.60) SLC6A5EPHX2CNR1
SCHEMBL16553206 0.96 CNR1 (0.60) SLC6A5EPHX2CNR1
SCHEMBL13561439 0.96 CNR1 (0.60) SLC6A5EPHX2CNR1
SCHEMBL24073302 0.92 LPAR3 (0.64) EPHX2LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150073038-A1 DELIVERY MOLECULES FOR THERAPEUTICS MARINA BIOTECH INC (US) 2015-03-12 — — US disclosed
EP-2496260-A1 ACTIVITY GENERATING DELIVERY MOLECULES Marina Biotech, Inc. (US) 2012-09-12 — — EP disclosed
WO-2011057020-A1 ACTIVITY GENERATING DELIVERY MOLECULES MARINA BIOTECH, INC. (US) 2011-05-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150073038-A1 DELIVERY MOLECULES FOR THERAPEUTICS LNPEP, LDLR, XPA SLC6A5 2329/4885EPHX2 2878/4885LPAR3 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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