Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10142076 | 1.00 | TMPRSS2 (0.36) | TMPRSS2ACVRL1PIK3CDTNK2LRRK2 | |
| SCHEMBL4970753 | 1.00 | TMPRSS2 (0.36) | TMPRSS2ACVRL1PIK3CDTNK2LRRK2 | |
| SCHEMBL24789794 | 0.85 | PIK3CD (0.34) | TMPRSS2PIK3CD | |
| SCHEMBL24512501 | 0.84 | POLRMT (0.32) | TMPRSS2PIK3CD | |
| SCHEMBL29566128 | 0.83 | TMPRSS2 (0.32) | TMPRSS2PIK3CD | |
| SCHEMBL24790497 | 0.83 | PIK3CD (0.33) | TMPRSS2PIK3CD | |
| SCHEMBL25608306 | 0.83 | PIK3CD (0.31) | PIK3CD | |
| SCHEMBL4972175 | 0.83 | PIK3CD (0.32) | PIK3CD | |
| SCHEMBL27121333 | 0.82 | TMPRSS2 (0.32) | TMPRSS2PIK3CD | |
| SCHEMBL23822912 | 0.82 | TNK2 (0.35) | TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239665-A1 | METHODS FOR TREATMENT OF VIRAL INFECTIONS INCLUDING SARS-COV-2 | GILEAD SCIENCES, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2021154687-A1 | METHODS FOR TREATING SARS COV-2 INFECTIONS | GILEAD SCIENCES, INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| EP-3785717-A1 | METHODS FOR TREATING CORONAVIRIDAE INFECTIONS | Gilead Sciences, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |
| WO-2017049060-A1 | METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |