SCHEMBL24512501

SCHEMBL24512501

N#C[C@]1(c2ccc3c(N)ncnn23)CC[C@@H](COP=O)O1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.32
▸ PIK3CD O00329 5/20 0.32
▸ TMPRSS2 O15393 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24789794 0.85 PIK3CD (0.34) PIK3CDTMPRSS2
SCHEMBL10141879 0.85 POLRMT (0.47) POLRMT
SCHEMBL10142076 0.84 TMPRSS2 (0.36) PIK3CDTMPRSS2
SCHEMBL4970753 0.84 TMPRSS2 (0.36) PIK3CDTMPRSS2
SCHEMBL18666907 0.84 TMPRSS2 (0.36) PIK3CDTMPRSS2
SCHEMBL24790497 0.84 PIK3CD (0.33) PIK3CDTMPRSS2
SCHEMBL29566128 0.84 TMPRSS2 (0.32) PIK3CDTMPRSS2
SCHEMBL25608306 0.83 PIK3CD (0.31) PIK3CD
SCHEMBL4972175 0.83 PIK3CD (0.32) PIK3CD
SCHEMBL27121333 0.83 TMPRSS2 (0.32) PIK3CDTMPRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230147364-A1 PROPHYLACTIC OR THERAPEUTIC AGENT FOR RNA VIRUS-RELATED DISEASES KYOTO UNIVERSITY (JP) 2023-05-11 — — US disclosed
WO-2022123501-A1 PROTECTED DEOXYDIDEHYDRO-NUCLEOSIDES VICTORIA LINK LIMITED (NZ) 2022-06-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230147364-A1 PROPHYLACTIC OR THERAPEUTIC AGENT FOR RNA VIRUS-RELATED DISEASES CYSLTR1, ALOX5, ALOX15 POLRMT 200/4885PIK3CD 4783/4885TMPRSS2 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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