Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21250362 | 0.91 | DRD2 (0.35) | DRD2HDAC1ABL1HDAC3HDAC6 | |
| SCHEMBL21250446 | 0.90 | DRD2 (0.36) | DRD2HDAC1ABL1HDAC3HDAC6 | |
| SCHEMBL21250436 | 0.88 | ROCK1 (0.41) | DRD2HDAC1ABL1HDAC3HDAC6 | |
| SCHEMBL21250438 | 0.88 | DRD2 (0.40) | DRD2HDAC1ABL1HDAC3HDAC6 | |
| SCHEMBL23018414 | 0.86 | DRD2 (0.38) | DRD2HDAC1ABL1HDAC3HDAC6 | |
| SCHEMBL21250324 | 0.85 | KDM1A (0.44) | DRD2HDAC1ABL1SMN1; SMN2EGLN1 | |
| SCHEMBL21939747 | 0.85 | DRD2 (0.40) | DRD2HDAC1HDAC3HDAC6SMN1; SMN2 | |
| SCHEMBL21250349 | 0.84 | DRD2 (0.35) | DRD2HDAC1ABL1HDAC3HDAC6 | |
| SCHEMBL21250465 | 0.84 | EGLN1 (0.42) | DRD2HDAC1HDAC3HDAC6EGLN1 | |
| SCHEMBL18667825 | 0.84 | HDAC1 (0.39) | DRD2HDAC1HDAC3HDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048950-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |