Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 6/20 | 0.49 |
| ▸ | ATP4B | P51164 | 6/20 | 0.49 |
| ▸ | AGER | Q15109 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23018555 | 0.89 | ATP4A (0.51) | ATP4AATP4BAGERHTTHRH3 | |
| SCHEMBL18667549 | 0.87 | ATP4A (0.41) | ATP4AATP4BAGER | |
| SCHEMBL26759163 | 0.87 | ATP4A (0.54) | ATP4AATP4BAGERHTTHRH3 | |
| SCHEMBL18666992 | 0.85 | KCNH2 (0.41) | AGERHRH3DRD3KDM4E | |
| SCHEMBL21229110 | 0.84 | ATP4A (0.48) | ATP4AATP4BAGERHRH3DRD2 | |
| SCHEMBL18667570 | 0.84 | HRH3 (0.44) | AGERHRH3 | |
| SCHEMBL18667102 | 0.84 | CXCR1 (0.36) | ATP4AATP4BAGERHRH3 | |
| Hydrochloric Acid SCHEMBL21229136 | 0.83 | ATP4A (0.52) | ATP4AATP4BAGERHTT | |
| Hydrochloric Acid SCHEMBL21229040 | 0.83 | ATP4A (0.52) | ATP4AATP4BAGERHTT | |
| SCHEMBL18667333 | 0.82 | CYP2C19 (0.36) | ATP4AATP4BAGERHTTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048950-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |