Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 2/20 | 0.36 |
| ▸ | ATP4A | P20648 | 8/20 | 0.36 |
| ▸ | ATP4B | P51164 | 8/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26759224 | 0.86 | ATP4A (0.41) | ATP4AATP4BLSSXIAPLMNA | |
| SCHEMBL18667553 | 0.85 | SIGMAR1 (0.34) | CYP2C19KCNH2LMNAMAPTRAB9A | |
| SCHEMBL21229079 | 0.85 | LTA4H (0.42) | ATP4AATP4BLSSLTA4HXIAP | |
| SCHEMBL18667570 | 0.85 | HRH3 (0.44) | CXCR1LSSLTA4HAGERHRH3 | |
| Hydrochloric Acid SCHEMBL20494013 | 0.84 | RAB9A (0.39) | CXCR1ATP4AATP4BLSSLTA4H | |
| SCHEMBL18667605 | 0.84 | ATP4A (0.49) | ATP4AATP4BAGERHRH3 | |
| SCHEMBL18667463 | 0.82 | LTA4H (0.40) | CXCR1ATP4AATP4BLSSLTA4H | |
| SCHEMBL21250320 | 0.81 | CA12 (0.41) | LTA4HXIAP | |
| SCHEMBL18667549 | 0.81 | ATP4A (0.41) | ATP4AATP4BAGER | |
| SCHEMBL18666990 | 0.80 | RAB9A (0.37) | XIAPCYP2C19KCNH2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017048950-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |