Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25639671 | 0.86 | PHGDH (0.39) | HRH3 | |
| SCHEMBL23712050 | 0.81 | SMN1; SMN2 (0.55) | HRH3 | |
| SCHEMBL21568056 | 0.77 | HRH3 (0.38) | HRH3 | |
| SCHEMBL21204595 | 0.75 | HRH3 (0.37) | HRH3 | |
| SCHEMBL3590803 | 0.74 | HRH3 (0.55) | HRH3 | |
| SCHEMBL19288816 | 0.74 | L3MBTL3 (0.44) | HRH3 | |
| SCHEMBL21739821 | 0.74 | L3MBTL3 (0.42) | — | |
| SCHEMBL18177695 | 0.74 | OPRL1 (0.39) | — | |
| SCHEMBL19313040 | 0.74 | KMT2A (0.45) | — | |
| SCHEMBL18177696 | 0.74 | OPRL1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017045750-A1 | COMPOUNDS AS ASIC INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |