Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18177695 | 0.87 | OPRL1 (0.39) | — | |
| SCHEMBL18177696 | 0.87 | OPRL1 (0.39) | — | |
| SCHEMBL18667948 | 0.86 | HRH3 (0.46) | HRH3 | |
| SCHEMBL21568056 | 0.86 | HRH3 (0.38) | PHGDHMGLLHRH3KCNH2MEN1 | |
| SCHEMBL19288816 | 0.83 | L3MBTL3 (0.44) | HRH3ALDH1A1KDM4EL3MBTL3L3MBTL1 | |
| SCHEMBL19313040 | 0.82 | KMT2A (0.45) | PHGDHMGLLKMT2A | |
| SCHEMBL7863270 | 0.79 | — | — | |
| SCHEMBL23367198 | 0.77 | TP53 (0.38) | PHGDHMGLLHRH3MEN1KMT2A | |
| SCHEMBL15508283 | 0.76 | CYP1A2 (0.52) | HRH3KCNH2POLBHSD17B10ALDH1A1 | |
| SCHEMBL19128943 | 0.76 | HRH3 (0.33) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198024-A1 | PYRAZOLE MAGL INHIBITORS | H. Lundbeck A/S (DK) | 2023-06-21 | — | — | EP | disclosed |