Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861193 | 0.85 | CYP17A1 (0.57) | CYP17A1CYP19A1MEN1KMT2ACYP3A4 | |
| SCHEMBL1859964 | 0.80 | CYP19A1 (0.46) | CYP17A1CYP19A1MEN1KMT2ACYP3A4 | |
| SCHEMBL1858766 | 0.77 | CYP17A1 (0.44) | CYP17A1CYP19A1MEN1KMT2ACYP3A4 | |
| SCHEMBL1864911 | 0.75 | CYP19A1 (0.53) | CYP17A1CYP19A1MEN1KMT2ACYP3A4 | |
| SCHEMBL1858497 | 0.71 | PGR (0.30) | CYP3A4PGRALDH1A1CYP2C19AR | |
| SCHEMBL23563828 | 0.71 | PGR (0.71) | CYP19A1MEN1KMT2ACYP3A4PGR | |
| SCHEMBL11873485 | 0.71 | CYP17A1 (0.69) | CYP17A1CYP19A1MEN1KMT2ACYP3A4 | |
| SCHEMBL18767708 | 0.71 | PGR (0.71) | CYP19A1MEN1KMT2ACYP3A4PGR | |
| SCHEMBL1859420 | 0.71 | CYP17A1 (0.69) | CYP17A1CYP19A1MEN1KMT2ACYP3A4 | |
| SCHEMBL18695522 | 0.71 | CYP17A1 (0.69) | CYP17A1CYP19A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154909-A1 | 1,4,6-androstatriene-3,17-dione (\"ATD\") for therapeutic uses | KNELLER BRUCE W | 2006-07-13 | — | — | US | claimed |
| US-7939517-B2 | 1,4,6-androstatriene-3,17-dione (“ATD”) for therapeutic uses | KNELLER BRUCE W | 2011-05-10 | — | — | US | disclosed |
| US-20060154909-A1 | 1,4,6-androstatriene-3,17-dione (\"ATD\") for therapeutic uses | KNELLER BRUCE W | 2006-07-13 | — | — | US | disclosed |