Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.30 |
| ▸ | AR | P10275 | 3/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1859330 | 0.85 | CYP17A1 (0.34) | PGRARNR3C2ALDH1A1CYP3A4 | |
| SCHEMBL1864539 | 0.80 | CYP19A1 (0.34) | PGRARNR3C2 | |
| SCHEMBL1862894 | 0.77 | — | — | |
| SCHEMBL1858576 | 0.75 | CYP19A1 (0.32) | PGRARNR3C2 | |
| SCHEMBL12638972 | 0.72 | AR (0.56) | PGRARNR3C2ALDH1A1CYP3A4 | |
| SCHEMBL1866920 | 0.71 | CYP17A1 (0.49) | PGRARALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL1859557 | 0.71 | CYP19A1 (0.46) | PGRARALDH1A1CYP3A4 | |
| SCHEMBL1864731 | 0.68 | SHBG (0.43) | ARALDH1A1CYP2C19 | |
| SCHEMBL1856536 | 0.68 | SHBG (0.35) | — | |
| SCHEMBL1864320 | 0.67 | ALDH1A1 (0.31) | PGRARALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154909-A1 | 1,4,6-androstatriene-3,17-dione (\"ATD\") for therapeutic uses | KNELLER BRUCE W | 2006-07-13 | — | — | US | claimed |
| US-7939517-B2 | 1,4,6-androstatriene-3,17-dione (“ATD”) for therapeutic uses | KNELLER BRUCE W | 2011-05-10 | — | — | US | disclosed |
| US-20060154909-A1 | 1,4,6-androstatriene-3,17-dione (\"ATD\") for therapeutic uses | KNELLER BRUCE W | 2006-07-13 | — | — | US | disclosed |