Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16575320 | 0.88 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ABCHEOPRM1 | |
| SCHEMBL10158872 | 0.88 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ABCHEOPRM1 | |
| SCHEMBL7865382 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ABCHEOPRM1 | |
| SCHEMBL1096325 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ABCHEOPRM1 | |
| SCHEMBL2308101 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ABCHEOPRM1 | |
| SCHEMBL24371821 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ABCHEOPRM1 | |
| SCHEMBL14929223 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ABCHEOPRM1 | |
| SCHEMBL18568726 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ABCHEOPRM1 | |
| SCHEMBL6839631 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ABCHEOPRM1 | |
| SCHEMBL10158814 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ABCHEOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603863-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2017-03-28 | — | — | US | disclosed |