Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158872 | 1.00 | ALDH1A1 (0.36) | ALDH1A1OPRM1OPRL1BCHEMEN1 | |
| SCHEMBL18671589 | 0.88 | ALDH1A1 (0.38) | ALDH1A1OPRM1OPRL1BCHEMEN1 | |
| SCHEMBL6839628 | 0.86 | TSHR (0.36) | ALDH1A1OPRM1OPRL1BCHEMEN1 | |
| SCHEMBL10158787 | 0.86 | ALDH1A1 (0.36) | ALDH1A1OPRM1OPRL1BCHEMEN1 | |
| SCHEMBL11981097 | 0.86 | ALDH1A1 (0.36) | ALDH1A1OPRM1OPRL1BCHEMEN1 | |
| SCHEMBL18561544 | 0.86 | ALDH1A1 (0.36) | ALDH1A1OPRM1OPRL1BCHEMEN1 | |
| SCHEMBL18503722 | 0.85 | GSTP1 (0.35) | ALDH1A1OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL16708499 | 0.85 | SLC6A2 (0.42) | GSTP1 | |
| SCHEMBL20959993 | 0.85 | SLC6A2 (0.42) | GSTP1 | |
| SCHEMBL22799571 | 0.84 | ALDH1A1 (0.38) | ALDH1A1OPRM1OPRL1BCHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230340008-A1 | BRIDGED NUCLEOSIDE AND NUCLEOTIDE USING SAME | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF HEALTH SCIENCES (JP) | 2023-10-26 | — | — | US | disclosed |
| US-9611479-B2 | Crosslinked nucleoside and nucleotide | OSAKA UNIVERSITY (JP) | 2017-04-04 | — | — | US | disclosed |
| US-20170044528-A1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | OSAKA UNIVERSITY (JP) | 2017-02-16 | — | — | US | disclosed |
| US-20150080457-A1 | 5' PHOSPHATE MIMICS | BANK OF AMERICA, N.A. | 2015-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080457-A1 | 5' PHOSPHATE MIMICS | NSUN2, RNGTT, RNMT | ALDH1A1 3467/4885OPRM1 4108/4885OPRL1 3797/4885 |
| US-20230340008-A1 | BRIDGED NUCLEOSIDE AND NUCLEOTIDE USING SAME | SLC29A1, SLC29A2, PNP | ALDH1A1 708/4885OPRM1 4031/4885OPRL1 3081/4885 |
| US-20170044528-A1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | NSUN2, NCL, NSUN3 | ALDH1A1 2297/4885OPRM1 2188/4885OPRL1 732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.