Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | PNP | P00491 | 1/20 | 0.49 |
| ▸ | KRAS | P01116 | 3/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17359759 | 1.00 | POLG (0.51) | POLGTGM2PNPKRASNT5E | |
| SCHEMBL16373906 | 0.94 | POLG (0.51) | POLGTGM2PNPKRASNT5E | |
| SCHEMBL17359754 | 0.94 | POLG (0.51) | POLGTGM2PNPKRASNT5E | |
| SCHEMBL19986613 | 0.93 | KRAS (0.53) | POLGTGM2PNPKRASNT5E | |
| SCHEMBL15070573 | 0.93 | POLG (0.50) | POLGTGM2PNPKRASNT5E | |
| SCHEMBL16368336 | 0.93 | KRAS (0.53) | POLGTGM2PNPKRASNT5E | |
| SCHEMBL16377302 | 0.91 | TGM2 (0.49) | POLGTGM2PNPKRASNT5E | |
| SCHEMBL17358530 | 0.90 | IMPDH2 (0.44) | POLGTGM2PNPKRASFUT5 | |
| SCHEMBL17359765 | 0.89 | TGM2 (0.47) | POLGTGM2PNPKRASNT5E | |
| SCHEMBL16373901 | 0.89 | TGM2 (0.47) | POLGTGM2PNPKRASNT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603863-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2017-03-28 | — | — | US | disclosed |