Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 10/20 | 0.62 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.33 |
| ▸ | SMO | Q99835 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16532673 | 0.90 | MAP3K14 (0.61) | MAP3K14SCN9AFFAR4SMO | |
| SCHEMBL16547238 | 0.85 | MAP3K14 (0.57) | MAP3K14SCN9AFFAR4SMO | |
| SCHEMBL18673546 | 0.83 | MAP3K14 (0.44) | MAP3K14SCN9AFFAR4ELANE | |
| SCHEMBL18673361 | 0.83 | MAP3K14 (0.43) | MAP3K14SCN9AFFAR4ELANE | |
| SCHEMBL18888035 | 0.82 | MAP3K14 (0.43) | MAP3K14SCN9AFFAR4ELANE | |
| SCHEMBL16516941 | 0.80 | MAP3K14 (0.52) | MAP3K14SCN9AFFAR4 | |
| SCHEMBL18673472 | 0.79 | MAP3K14 (0.42) | MAP3K14SCN9AELANE | |
| SCHEMBL16547159 | 0.78 | MAP3K14 (0.85) | MAP3K14 | |
| SCHEMBL16534276 | 0.78 | MAP3K14 (1.00) | MAP3K14 | |
| SCHEMBL16516848 | 0.78 | MAP3K14 (1.00) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145034-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | GENENTECH, INC. (US) | 2017-05-25 | — | — | US | disclosed |
| US-9605005-B2 | Alkynyl alcohols and methods of use | GENENTECH, INC. (US) | 2017-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145034-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | NFKB2, NFKB1, RELA | MAP3K14 514/4885SCN9A 760/4885FFAR4 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.