Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309150 | 1.00 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP2C19HIF1AEPAS1 | |
| SCHEMBL5604863 | 1.00 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP2C19HIF1AEPAS1 | |
| SCHEMBL22283484 | 0.90 | CYP2D6 (0.45) | CYP1A2CYP2D6CYP2C19HIF1AEPAS1 | |
| SCHEMBL22283486 | 0.90 | CYP2D6 (0.45) | CYP1A2CYP2D6CYP2C19HIF1AEPAS1 | |
| SCHEMBL22283451 | 0.88 | HIF1A (0.50) | CYP1A2CYP2D6CYP2C19HIF1AEPAS1 | |
| SCHEMBL28574014 | 0.88 | HIF1A (0.43) | CYP1A2HIF1AEPAS1ALOX15TSHR | |
| SCHEMBL30136443 | 0.87 | CYP1A2 (0.35) | CYP1A2CYP2D6CYP2C19HIF1AEPAS1 | |
| SCHEMBL6889733 | 0.86 | HIF1A (0.40) | CYP1A2HIF1AEPAS1ALOX15TSHR | |
| SCHEMBL29410313 | 0.85 | HIF1A (0.40) | CYP1A2CYP2D6CYP2C19HIF1AEPAS1 | |
| SCHEMBL15457608 | 0.84 | ALOX15 (0.41) | CYP1A2CYP2D6CYP2C19HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496682-A1 | DELIVERY PARTICLE | The Procter & Gamble Company (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011056935-A1 | DELIVERY PARTICLE | THE PROCTER & GAMBLE COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |