Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574014 | 0.95 | HIF1A (0.43) | HIF1AEPAS1TSHRCYP3A4ICMT | |
| SCHEMBL28426287 | 0.88 | ALOX15 (0.44) | HIF1AEPAS1CYP3A4LMNAALOX15 | |
| SCHEMBL22283458 | 0.88 | LMNA (0.41) | HIF1AEPAS1TSHRCYP3A4LMNA | |
| SCHEMBL447073 | 0.86 | ALDH1A1 (0.46) | HIF1AEPAS1TSHRCYP3A4POLB | |
| SCHEMBL5604863 | 0.86 | CYP1A2 (0.44) | HIF1AEPAS1TSHRCYP3A4LMNA | |
| SCHEMBL309150 | 0.86 | CYP1A2 (0.44) | HIF1AEPAS1TSHRCYP3A4LMNA | |
| SCHEMBL1867355 | 0.86 | CYP1A2 (0.44) | HIF1AEPAS1TSHRCYP3A4LMNA | |
| SCHEMBL29483202 | 0.84 | KDM4E (0.46) | HIF1AEPAS1LMNACYP1A2POLB | |
| SCHEMBL30096463 | 0.84 | ADRB2 (0.41) | HIF1AEPAS1TSHRCYP3A4GMNN | |
| SCHEMBL30136443 | 0.84 | CYP1A2 (0.35) | HIF1AEPAS1TSHRCYP3A4ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-1373368-B1 | COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE COMPOUNDS | FIRMENICH & CIE (CH) | 2013-02-27 | — | — | EP | disclosed |
| US-20040048754-A1 | Compounds for a controlled release of active compounds | FIRMENICH SA (CH) | 2004-03-11 | — | — | US | disclosed |
| EP-1373368-A1 | COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE COMPOUNDS | FIRMENICH SA (CH) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002077074-A1 | COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE COMPOUNDS | FIRMENICH SA (CH) | 2002-10-03 | — | — | WO | disclosed |