Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.40 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 13/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 4/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18681117 | 0.88 | PIN1 (0.52) | PIN1PEPDXPNPEP1DPP4DPP8 | |
| SCHEMBL18675241 | 0.84 | ATM (0.44) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL18675242 | 0.84 | ATM (0.44) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL18675236 | 0.77 | PREP (0.41) | PEPDDPP4DPP8DPP9FAP | |
| SCHEMBL17282582 | 0.76 | PIN1 (0.63) | PIN1PEPDXPNPEP1DPP4DPP8 | |
| SCHEMBL18675244 | 0.75 | PSMB9 (0.35) | DPP4DPP8FAPPSMB9DPP7 | |
| SCHEMBL18675240 | 0.74 | PREP (0.49) | PEPDDPP4DPP8DPP9FAP | |
| SCHEMBL18675250 | 0.73 | PREP (0.45) | PEPDFAPPREPKDM4EALDH1A1 | |
| SCHEMBL18675248 | 0.73 | ACE (0.43) | DPP4DPP8FAPDPP7PREP | |
| SCHEMBL18681034 | 0.72 | ATM (0.40) | PIN1PEPDDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088582-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088582-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | PIN1 834/4885PEPD 2/4885XPNPEP1 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.