Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 6/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | VHL | P40337 | 3/20 | 0.32 |
| ▸ | ELOC | Q15369 | 3/20 | 0.32 |
| ▸ | ELOB | Q15370 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18675242 | 1.00 | ATM (0.44) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL18681034 | 0.87 | ATM (0.40) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL18681155 | 0.87 | ATM (0.40) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL18675243 | 0.84 | PIN1 (0.42) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL25603210 | 0.79 | ATM (0.45) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL18675236 | 0.78 | PREP (0.41) | DPP4DPP8DPP9FAPALDH1A1 | |
| SCHEMBL15110224 | 0.77 | ATM (0.63) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL15110041 | 0.77 | ATM (0.63) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL15110042 | 0.77 | ATM (0.63) | ATMPIK3CDDPP4DPP8DPP9 | |
| SCHEMBL16267049 | 0.77 | ATM (0.63) | ATMPIK3CDDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088582-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088582-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | ATM 2604/4885PIK3CD 3033/4885DPP4 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.