Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ODC1 | P11926 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978332 | 1.00 | GGT1 (0.32) | GGT1MEN1ALDH1A1CYP1A2THRB | |
| SCHEMBL28674776 | 0.80 | FDPS (0.41) | GGT1MEN1ALDH1A1CYP1A2THRB | |
| SCHEMBL288789 | 0.80 | FDPS (0.41) | GGT1MEN1ALDH1A1CYP1A2THRB | |
| SCHEMBL2341824 | 0.75 | — | — | |
| SCHEMBL8984248 | 0.74 | — | — | |
| SCHEMBL6931218 | 0.71 | PAOX (0.32) | ODC1 | |
| SCHEMBL940519 | 0.71 | PAOX (0.32) | ODC1 | |
| SCHEMBL600714 | 0.70 | — | — | |
| SCHEMBL600715 | 0.70 | — | — | |
| SCHEMBL27800247 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3146977-A1 | TFPI INHIBITORS AND METHODS OF USE | Baxalta GmbH (CH) | 2017-03-29 | — | — | EP | disclosed |