SCHEMBL1867684

SCHEMBL1867684

CCCCCCCC/C=C\CCCCCCC(C(=O)CCCCCCCCCCCCC)C(=O)C(OP(=O)(O)OCCN)[C@@H](O)CO

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 8/20 0.42
GPR34 Q9UPC5 4/20 0.42
GPR174 Q9BXC1 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1864332 1.00 P2RY10 (0.42) P2RY10GPR34GPR174
SCHEMBL2329616 1.00 P2RY10 (0.42) P2RY10GPR34GPR174
SCHEMBL8504216 0.89 P2RY10 (0.45) P2RY10GPR34GPR174
SCHEMBL6372215 0.83 PLA2G2C (0.46) P2RY10GPR34GPR174
SCHEMBL15022342 0.83 PLA2G2C (0.46) P2RY10GPR34GPR174
SCHEMBL1899888 0.81 PRKCA (0.45) P2RY10GPR34
SCHEMBL1900343 0.81 PRKCA (0.45) P2RY10GPR34
SCHEMBL1556453 0.81 PRKCA (0.45) P2RY10GPR34
SCHEMBL8628861 0.80 P2RY10 (0.43) P2RY10GPR34
SCHEMBL16964730 0.79 P2RY10 (0.43) P2RY10GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2350296-A1 BRANCHED CATIONIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEM Enzon Pharmaceuticals, Inc. (US) 2011-08-03 EP disclosed
WO-2010057160-A9 RELEASABLE FUSOGENIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS ENZON PHARMACEUTICALS, INC. (US) 2011-05-05 WO disclosed
WO-2010056403-A1 BRANCHED CATIONIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEM ENZON PHARMACEUTICALS, INC. (US) 2010-05-20 WO disclosed