SCHEMBL15022342

SCHEMBL15022342

CCCCCCCCCCCCCCCCCC(=O)C(OP(=O)(O)OCCN)[C@@H](O)CO

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 2/20 0.46
P2RY10 O00398 6/20 0.39
GPR34 Q9UPC5 2/20 0.39
GPR174 Q9BXC1 2/20 0.39
PLA2G2D Q9UNK4 1/20 0.37
LPAR6 P43657 1/20 0.37
LPAR1 Q92633 1/20 0.37
LPAR4 Q99677 1/20 0.37
LPAR5 Q9H1C0 1/20 0.37
LPAR2 Q9HBW0 1/20 0.37
LPAR3 Q9UBY5 1/20 0.37
ENPP2 Q13822 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6372215 1.00 PLA2G2C (0.46) PLA2G2CP2RY10GPR34GPR174PLA2G2D
SCHEMBL8504216 0.93 P2RY10 (0.45) P2RY10GPR34GPR174LPAR1LPAR3
SCHEMBL6334072 0.88 PLA2G2C (0.35) PLA2G2CP2RY10GPR174
SCHEMBL9951880 0.86 PLA2G2C (0.45) PLA2G2CP2RY10GPR34GPR174PLA2G2D
SCHEMBL9951445 0.86 PLA2G2C (0.45) PLA2G2CP2RY10GPR34GPR174PLA2G2D
SCHEMBL4737508 0.86 PLA2G2C (0.45) PLA2G2CP2RY10GPR34GPR174PLA2G2D
SCHEMBL27092071 0.84 KDM4E (0.48) P2RY10GPR34GPR174LPAR6LPAR1
Monoethanolamine SCHEMBL27656115 0.84 PTPN1 (0.46) LPAR6LPAR1LPAR4LPAR5LPAR2
SCHEMBL18797278 0.83 PLA2G2C (0.35) PLA2G2CP2RY10GPR34GPR174LPAR6
SCHEMBL2329616 0.83 P2RY10 (0.42) P2RY10GPR34GPR174

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023240156-A9 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES, AND METHODS OF SYNTHESIS AND USE THEREOF TIDAL THERAPEUTICS, INC. (US) 2024-04-18 WO claimed
US-20200297874-A1 METHOD AND DEVICE FOR PRODUCING OPTIMIZED LIPID-BASED MICRO/NANO-BUBBLES TRUST BIO SONICS INC (TW) 2020-09-24 US claimed
US-20170360933-A1 NUCLEIC ACID, MEDICAL NANOPARTICLE, AND PHARMACEUTICAL COMPOSITION THEREOF CHUNG YUAN CHRISTIAN UNIVERSITY (TW) 2017-12-21 US claimed
WO-2023240156-A9 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES, AND METHODS OF SYNTHESIS AND USE THEREOF TIDAL THERAPEUTICS, INC. (US) 2024-04-18 WO disclosed
US-20230295628-A1 NUCLEIC ACID COMPLEX NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY (JP) 2023-09-21 US disclosed
US-20230277457-A1 METHODS OF PREPARING LIPID NANOPARTICLES ARES CAPITAL CORPORATION, AS AGENT 2023-09-07 US disclosed
US-20230263905-A1 SONOSENSITIVE LIPOSOME AND METHOD FOR PREPARING SAME IMGT CO, LTD. (KR) 2023-08-24 US disclosed
US-20230173104-A1 LNP COMPOSITIONS COMPRISING AN MRNA THERAPEUTIC AND AN EFFECTOR MOLECULE ARES CAPITAL CORPORATION, AS AGENT 2023-06-08 US disclosed
US-11654109-B2 Cavitation seed for drug delivery, and drug delivery method using same PACIFIC SYSTEM CO., LTD. (KR) 2023-05-23 US disclosed
US-11648260-B2 Vesicles comprising a PTEN inhibitor and uses of same TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITTED (IL) 2023-05-16 US disclosed
US-20230126953-A1 IONIZABLE CATIONIC LIPIDS AKAGERA MEDICINES, INC. (US) 2023-04-27 US disclosed
US-20190022019-A1 POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE MODERNATX INC (US) 2019-01-24 US disclosed
US-20180289838-A1 POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE ARES CAPITAL CORPORATION, AS AGENT 2018-10-11 US disclosed
US-20180271795-A1 POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE ARES CAPITAL CORPORATION, AS AGENT 2018-09-27 US disclosed
US-20180066256-A1 RNA Modulating Oligonucleotides with Improved Characteristics for the Treatment of Neuromuscular Disorders BIOMARIN TECH BV (NL) 2018-03-08 US disclosed
US-9861707-B2 Treating bladder tumor cells using fibronectin attachment protein as a target PURDUE RESEARCH FOUNDATION (US) 2018-01-09 US disclosed
US-9744130-B2 Cationic dry powders PULMATRIX OPERATING COMPANY, INC. (US) 2017-08-29 US disclosed
US-20170095568-A1 TREATING BLADDER TUMOR CELLS USING FIBRONECTIN ATTACHMENT PROTEIN AS A TARGET PURDUE RESEARCH FOUNDATION 2017-04-06 US disclosed
US-20170020813-A1 CATIONIC DRY POWDERS PULMATRIX OPERATING COMPANY, INC. (US) 2017-01-26 US disclosed
US-20130156851-A1 LIPOMACROCYCLES AND USES THEREOF AGAVE PHARMA, INCORPORATED 2013-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230173104-A1 LNP COMPOSITIONS COMPRISING AN MRNA THERAPEUTIC AND AN EFFECTOR MOLECULE SNRPE, SNRPB2, SNRPF PLA2G2C 720/4885P2RY10 4095/4885GPR34 4187/4885
US-20230263905-A1 SONOSENSITIVE LIPOSOME AND METHOD FOR PREPARING SAME SON, CLPTM1L, SMPD1 PLA2G2C 1078/4885P2RY10 3044/4885GPR34 3478/4885
US-20170020813-A1 CATIONIC DRY POWDERS SLC30A5, SLC26A3, EXOSC9 PLA2G2C 106/4885P2RY10 405/4885GPR34 2100/4885
US-20180289838-A1 POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE POLM, EMG1, MCM6 PLA2G2C 2780/4885P2RY10 4468/4885GPR34 4631/4885
US-20230295628-A1 NUCLEIC ACID COMPLEX POLRMT, SNRPE, FABP7 PLA2G2C 882/4885P2RY10 4084/4885GPR34 1999/4885
US-20130156851-A1 LIPOMACROCYCLES AND USES THEREOF LIPC, LIPA, LIPE PLA2G2C 462/4885P2RY10 3713/4885GPR34 742/4885
US-20230126953-A1 IONIZABLE CATIONIC LIPIDS PHOSPHO1, LIPA, ABHD16A PLA2G2C 59/4885P2RY10 3003/4885GPR34 3406/4885
US-20230277457-A1 METHODS OF PREPARING LIPID NANOPARTICLES PLTP, LIPA, CETP PLA2G2C 160/4885P2RY10 2906/4885GPR34 4832/4885
US-20190022019-A1 POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE POLM, EMG1, MCM6 PLA2G2C 2780/4885P2RY10 4468/4885GPR34 4631/4885
US-20180271795-A1 POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE POLM, EMG1, MCM6 PLA2G2C 2780/4885P2RY10 4468/4885GPR34 4631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.