Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18679252 | 1.00 | ENPP3 (0.33) | ENPP3MAPTNR3C1NR1I3ALDH1A1 | |
| SCHEMBL18684193 | 0.98 | ENPP3 (0.33) | ENPP3MAPTNR3C1NR1I3ALDH1A1 | |
| SCHEMBL18679254 | 0.98 | MAPT (0.34) | ENPP3MAPTNR3C1NR1I3ALDH1A1 | |
| SCHEMBL18679649 | 0.97 | MAPT (0.33) | ENPP3MAPTNR3C1NR1I3ALDH1A1 | |
| SCHEMBL18679651 | 0.97 | MAPT (0.33) | ENPP3MAPTNR3C1NR1I3ALDH1A1 | |
| SCHEMBL18679315 | 0.97 | MAPT (0.34) | MAPTNR3C1NR1I3ALDH1A1MEN1 | |
| SCHEMBL18679669 | 0.96 | MAPT (0.34) | MAPTNR3C1NR1I3ALDH1A1MEN1 | |
| SCHEMBL18679258 | 0.95 | MAPT (0.33) | ENPP3MAPTNR3C1NR1I3ALDH1A1 | |
| SCHEMBL18679335 | 0.95 | MAPT (0.33) | ENPP3MAPTNR3C1NR1I3ALDH1A1 | |
| SCHEMBL18679253 | 0.95 | MAPT (0.33) | ENPP3MAPTNR3C1NR1I3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170092872-A1 | ORGANIC LIGHT-EMITTING DEVICE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2017-03-30 | — | — | US | disclosed |
| US-20170092872-A1 | ORGANIC LIGHT-EMITTING DEVICE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170092872-A1 | ORGANIC LIGHT-EMITTING DEVICE | OR10J3, L1CAM, EML4 | ENPP3 1571/4885MAPT 1197/4885NR3C1 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.