Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18679334 | 0.99 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL18679688 | 0.97 | NR1I3 (0.33) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL18679748 | 0.96 | NR1I3 (0.34) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL18679381 | 0.94 | NR1I3 (0.34) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL18679224 | 0.93 | MEN1 (0.35) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL18679302 | 0.92 | MEN1 (0.36) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL18679269 | 0.91 | MAPT (0.34) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL18679285 | 0.91 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL18684110 | 0.90 | — | — | |
| SCHEMBL18679329 | 0.90 | KMT2A (0.34) | ALDH1A1MEN1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170092872-A1 | ORGANIC LIGHT-EMITTING DEVICE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2017-03-30 | — | — | US | disclosed |
| US-20170092872-A1 | ORGANIC LIGHT-EMITTING DEVICE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170092872-A1 | ORGANIC LIGHT-EMITTING DEVICE | OR10J3, L1CAM, EML4 | ALDH1A1 50/4885MEN1 1002/4885KMT2A 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.