SCHEMBL1867931

SCHEMBL1867931

CCCCCCc1ccc(OC(C)=O)cc1.[NaH]

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 6/20 0.66
THRA P10827 5/20 0.66
ALDH1A1 P00352 4/20 0.53
ESR1 P03372 2/20 0.53
ADRA2A P08913 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
TACR2 P21452 2/20 0.53
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
LMNA P02545 2/20 0.53
CYP3A4 P08684 2/20 0.53
KDM4E B2RXH2 1/20 0.53
SHBG P04278 1/20 0.53
TP53 P04637 1/20 0.53
HSPD1 P10809 1/20 0.53
ADRB3 P13945 1/20 0.53
HTR2C P28335 1/20 0.53
HSPE1 P61604 1/20 0.53
HIF1A Q16665 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10775670 1.00 THRB (0.66) THRBTHRAALDH1A1ESR1ADRA2A
SCHEMBL7930197 0.98 THRB (0.68) THRBTHRAALDH1A1ESR1ADRA2A
SCHEMBL8072596 0.98 THRB (0.68) THRBTHRAALDH1A1ESR1ADRA2A
SCHEMBL8080349 0.98 THRB (0.68) THRBTHRAALDH1A1ESR1ADRA2A
SCHEMBL8086401 0.98 THRB (0.68) THRBTHRAALDH1A1ESR1ADRA2A
SCHEMBL3043815 0.98 THRB (0.68) THRBTHRAALDH1A1ESR1ADRA2A
SCHEMBL1248565 0.98 THRB (0.68) THRBTHRAALDH1A1ESR1ADRA2A
SCHEMBL1810213 0.97 THRB (0.69) THRBTHRAALDH1A1ESR1ADRA2A
SCHEMBL9224060 0.94 THRB (0.62) THRBTHRAALDH1A1ESR1ADRA2A
SCHEMBL1415501 0.91 THRB (0.61) THRBTHRAALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120302487-A1 COMPOSITE REVOLYMER LIMITED (GB) 2012-11-29 US claimed
EP-2494024-A1 COMPOSITE Revolymer Limited (GB) 2012-09-05 EP claimed
WO-2011051681-A1 COMPOSITE REVOLYMER LIMITED (GB) 2011-05-05 WO claimed
US-20140171327-A1 NOVEL COMPOSITE REVOLYMER (U.K.) LIMITED (GB) 2014-06-19 US disclosed
EP-2697355-A1 PARTICLES WITH HYDROXYL VINYLIC COPOLYMER COATING SENSITIVE TO IONIC STRENGTH Revolymer Limited (GB) 2014-02-19 EP disclosed
US-20120302487-A1 COMPOSITE REVOLYMER LIMITED (GB) 2012-11-29 US disclosed
WO-2012140442-A1 PARTICLES WITH HYDROXYL VINYLIC COPOLYMER COATING SENSITIVE TO IONIC STRENGTH REVOLYMER LIMITED (GB) 2012-10-18 WO disclosed
EP-2494024-A1 COMPOSITE Revolymer Limited (GB) 2012-09-05 EP disclosed
WO-2011051681-A1 COMPOSITE REVOLYMER LIMITED (GB) 2011-05-05 WO disclosed
EP-0062523-B1 DETERGENT ADDITIVE COMPOSITIONS AND PREPARATIONS AND USE THEREOF IN DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1987-12-09 EP disclosed
US-4678594-A WATER-SOLUBLE NONIONIC SURFACTANT COLGATE-PALMOLIVE COMPANY (US) 1987-07-07 US disclosed
EP-0063017-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-20 EP disclosed
EP-0062523-A2 Detergent additive compositions and preparations and use thereof in detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-13 EP disclosed
EP-0051987-A1 Bleach activator compositions, preparation thereof and use in granular detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-05-19 EP disclosed
US-4321157-A SILICA OR SILICATE, ORGANIC PEROXY ACID BLEACH PRECURSOR, ALIPHATIC ALCOHOL-ALKYLENE OXIDE CONDENSATE NONIONIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1982-03-23 US disclosed
EP-0034387-A2 Mulls containing chain structure clay suspension aids THE PROCTER & GAMBLE COMPANY (US) 1981-08-26 EP disclosed
EP-0028432-A1 Granular laundry compositions THE PROCTER & GAMBLE COMPANY (US) 1981-05-13 EP disclosed
US-4264466-A LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY (US) 1981-04-28 US disclosed
US-4248928-A TETRAACETYL AKYLENEDIAMINES OR TETRAACETYL GLYCOURIL PEROXY BLEACH PRECURSOR THE PROCTER & GAMBLE COMPANY (US) 1981-02-03 US disclosed
US-4179390-A Laundry additive product THE PROCTER & GAMBLE COMPANY (US) 1979-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140171327-A1 NOVEL COMPOSITE PUF60, C5, VCL THRB 4456/4885THRA 3805/4885ALDH1A1 3641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.