SCHEMBL1415501

SCHEMBL1415501

CCCCc1ccc(OC(C)=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.61
THRA P10827 2/20 0.58
ALDH1A1 P00352 2/20 0.55
HPGD P15428 1/20 0.55
HSD17B10 Q99714 1/20 0.55
LMNA P02545 1/20 0.52
RARB P10826 1/20 0.50
POLB P06746 1/20 0.50
PLK1 P53350 1/20 0.50
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1810213 0.95 THRB (0.69) THRBTHRAALDH1A1HSD17B10LMNA
SCHEMBL8086401 0.93 THRB (0.68) THRBTHRAALDH1A1HSD17B10LMNA
SCHEMBL8072596 0.93 THRB (0.68) THRBTHRAALDH1A1HSD17B10LMNA
SCHEMBL7930197 0.93 THRB (0.68) THRBTHRAALDH1A1HSD17B10LMNA
SCHEMBL1248565 0.93 THRB (0.68) THRBTHRAALDH1A1HSD17B10LMNA
SCHEMBL3043815 0.93 THRB (0.68) THRBTHRAALDH1A1HSD17B10LMNA
SCHEMBL8080349 0.93 THRB (0.68) THRBTHRAALDH1A1HSD17B10LMNA
SCHEMBL1867931 0.91 THRB (0.66) THRBTHRAALDH1A1HSD17B10LMNA
SCHEMBL10775670 0.91 THRB (0.66) THRBTHRAALDH1A1HSD17B10LMNA
SCHEMBL23894744 0.90 LMNA (0.57) THRBTHRAALDH1A1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257845-B1 METHOD OF PRODUCING VARIEGATED PLANTS Taguchi, Masayasu (JP) 1991-10-16 EP claimed
EP-0257845-A2 Method of producing variegated plants Taguchi, Masayasu (JP) 1988-03-02 EP claimed
EP-4501125-A2 MIXTURES CONTAINING (E)-3-BENZO[1, 3 -DIOXOL-5-YL-N,N-DIPHENYL-2-PROPENAMIDE Symrise AG (DE) 2025-02-05 EP disclosed
EP-3663366-B1 USE OF PHYSIOLOGICAL COOLING INGREDIENTS AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS SYMRISE AG (DE) 2025-01-08 EP disclosed
EP-3496698-B1 MIXTURES COMPRISING (3)-BENZO(1,3)DIOXOL-5-YL-N,N-DIPHENYLE-2-PROPENAMIDE SYMRISE AG (DE) 2024-11-20 EP disclosed
US-10980727-B2 Mixtures containing (E)-3-benzo[1,3]dioxol-5-yl-N,N-diphenyl-2-propenamide SYMRISE AG (DE) 2021-04-20 US disclosed
CN-110981720-B Diaryl acetate compound and preparation method thereof 河南大学 2020-11-03 CN disclosed
CN-110981720-A Diaryl acetate compound and preparation method thereof 河南大学 2020-04-10 CN disclosed
EP-2249426-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEM CORP (JP) 2019-07-10 EP disclosed
US-20190167553-A1 MIXTURES CONTAINING (E)-3-BENZO[1,3]DIOXOL-5-YL-N,N-DIPHENYL-2-PROPENAMIDE SYMRISE AG (DE) 2019-06-06 US disclosed
US-9963472-B2 Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (PKAN) and methods for the synthesis of such compounds ACIES BIO D.O.O. (SI) 2018-05-08 US disclosed
CN-1197450-A Esters and amides as phospholipase A2 inhibitors FUJISAWA PHARMACEUTICAL CO (JP) 1998-10-28 CN disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed
EP-0313284-B1 2,5-Diphenyl pyrimidine compounds and liquid crystal compositions containing them CHISSO CORP (JP) 1994-07-27 EP disclosed
EP-0257845-B1 METHOD OF PRODUCING VARIEGATED PLANTS Taguchi, Masayasu (JP) 1991-10-16 EP disclosed
EP-0313284-A2 2,5-Diphenyl pyrimidine compounds and liquid crystal compositions containing them Chisso Corporation (JP) 1989-04-26 EP disclosed
EP-0257845-A2 Method of producing variegated plants Taguchi, Masayasu (JP) 1988-03-02 EP disclosed
US-4234733-A PHENOL, ALIPHATIC ESTER OR ETHER, CARBON MONOXIDE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1980-11-18 US disclosed
US-4113362-A LIGHT VALVE, LIGHT VALVE SUSPENSION MATERIALS AND SUSPENSION THEREFOR RESEARCH FRONTIERS INCORPORATED (US) 1978-09-12 US disclosed
US-4113362-A LIGHT VALVE, LIGHT VALVE SUSPENSION MATERIALS AND SUSPENSION THEREFOR RESEARCH FRONTIERS INCORPORATED (US) 1978-09-12 US disclosed