SCHEMBL186794

SCHEMBL186794

O=C(Cl)c1ccc(CCl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.64
CA2 P00918 2/20 0.64
ALDH1A1 P00352 7/20 0.45
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
GSK3B P49841 2/20 0.38
POLB P06746 3/20 0.37
MAPT P10636 3/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
THRB P10828 2/20 0.36
THRA P10827 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
HIF1A Q16665 2/20 0.35
KDM4E B2RXH2 1/20 0.35
USP2 O75604 1/20 0.35
GAA P10253 1/20 0.35
NR4A1 P22736 1/20 0.35
APEX1 P27695 1/20 0.35
APOBEC3A P31941 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL19042854 0.91 CA1 (0.55) CA1CA2ALDH1A1KMT2AMEN1
SCHEMBL25627685 0.88 CA1 (0.52) CA1CA2ALDH1A1KMT2AMAPT
Tetrahydrofuran SCHEMBL28622884 0.84 CA1 (0.48) CA1CA2ALDH1A1KMT2AMAPT
Benzoyl Chloride SCHEMBL28100655 0.84 ALDH1A1 (0.50) CA1CA2ALDH1A1KMT2AMEN1
Methylene Chloride SCHEMBL29223376 0.84 ALDH1A1 (0.52) CA1CA2ALDH1A1GSK3BMAPT
SCHEMBL1290930 0.82 KMT2A (0.58) CA1CA2ALDH1A1KMT2ASMN1; SMN2
SCHEMBL7132233 0.82 HDAC1 (0.47) CA1CA2ALDH1A1KMT2APOLB
SCHEMBL1559089 0.82 CA1 (0.67) CA1CA2ALDH1A1KMT2AMAPT
SCHEMBL3077841 0.81 CA1 (0.43) CA1CA2ALDH1A1KMT2AMEN1
SCHEMBL3962189 0.81 CA1 (0.43) CA1CA2ALDH1A1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2015 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192315-A Echinococcosis-resistant medicine and preparation method and application thereof 新疆医科大学 2025-06-24 CN claimed
CN-116023648-B Polyethylene glycol-RakicidinB 1 derivative and preparation method and application thereof 福建省微生物研究所 2025-06-17 CN claimed
CN-119564549-B Avocado cleansing cream containing modified avocado oil additive 上海正喧品牌管理有限公司 2025-05-16 CN claimed
CN-119993602-A Carbon nano composite conductive material and application thereof in cable shielding layer 碳境科技(广东)有限公司 2025-05-13 CN claimed
CN-119874605-A Benzoyl piperidinyl piperidine derivatives, preparation method and application thereof 南通大学 2025-04-25 CN claimed
CN-119798229-A Preparation method of imatinib dimer 中国食品药品检定研究院 2025-04-11 CN claimed
CN-119055823-B Preparation method of degradable hemostatic gel dressing 浙江奥奇医用敷料有限公司 2025-04-08 CN claimed
CN-119613035-A High-strength multicomponent concrete and preparation method thereof 江苏旺材科技有限公司 2025-03-14 CN claimed
CN-119564549-A Avocado cleansing cream containing modified avocado oil additive 上海正喧品牌管理有限公司 2025-03-07 CN claimed
CN-119330950-A Tumor targeting near-infrared copper ion fluorescent probe and preparation and application thereof 中国人民解放军空军军医大学 2025-01-21 CN claimed
CN-101544795-A Polystyrene/two-dimensional silica compound and preparation method thereof UNIV SHANGHAI 2009-09-30 CN claimed
EP-2007739-A2 A CONVERGENT PROCESS FOR THE SYNTHESIS OF TAXANE DERIVATIVES Tapestry Pharmaceuticals, Inc. (US) 2008-12-31 EP claimed
US-20080194819-A1 Process For Preparation of Imatinib Base INSTYTUT FARMACEUTYCZNY (PL) 2008-08-14 US claimed
WO-2007126893-A2 A CONVERGENT PROCESS FOR THE SYNTHESIS OF TAXANE DERIVATIVES TAPESTRY PHARMACEUTICALS, INC. (US) 2007-11-08 WO claimed
US-20070225510-A1 Convergent Process for the Synthesis of Taxane Derivatives TAPESTRY PHARMACEUTICALS, INC. 2007-09-27 US claimed
EP-1833815-A2 A PROCESS FOR PREPARATION OF IMATINIB BASE INSTYTUT FARMACEUTYCZNY (PL) 2007-09-19 EP claimed
WO-2006071130-A2 A PROCESS FOR PREPARATION OF IMATINIB BASE INSTYTUT FARMACEUTYCZNY (PL) 2006-07-06 WO claimed
CN-1706840-A Methylsulfonate of pyrimidine derivative and its prepn process, application and medicine composition HONGZHOU XINRUIJIA BIOMEDICINE (CN) 2005-12-14 CN claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
US-5821287-A SPIROOXAZINE PIGMENT CONTAINING DOUBLE BOND BLENDED WITH A POLYMER OR FORMS A COPOLYMER WITH UNSATURATED MONOMERS, TO FORM HIGH MOLECULAR WEIGHT PHOTOCHROMIC MATERIAL USEFUL FOR PHOTOCHROMIC EYE GLASSES OR COATING NATIONAL SCIENCE COUNCIL (TW) 1998-10-13 US claimed