SCHEMBL18680259

SCHEMBL18680259

CCCCCCCCc1ccc(N(c2ccc(/C=C/C=C/c3ccccc3)cc2)c2ccc(/C=C/C=C/c3ccccc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.48
HTR2A P28223 2/20 0.46
CYSLTR2 Q9NS75 3/20 0.45
CYSLTR1 Q9Y271 3/20 0.45
TRPA1 O75762 1/20 0.45
TRPM2 O94759 1/20 0.45
PLA2G1B P04054 1/20 0.45
TRPM8 Q7Z2W7 1/20 0.45
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
LPL P06858 4/20 0.44
LIPG Q9Y5X9 4/20 0.44
TRPV1 Q8NER1 1/20 0.44
MGLL Q99685 1/20 0.44
ESR1 P03372 2/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A2 P23975 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12680109 1.00 KCNH2 (0.48) KCNH2HTR2ACYSLTR2CYSLTR1TRPA1
SCHEMBL19871000 0.98 CYSLTR2 (0.46) KCNH2HTR2ACYSLTR2CYSLTR1TRPA1
SCHEMBL18680247 0.95 KCNH2 (0.43) KCNH2HTR2ACYSLTR2CYSLTR1TRPA1
SCHEMBL18680244 0.95 KCNH2 (0.43) KCNH2HTR2ACYSLTR2CYSLTR1TRPA1
SCHEMBL10013199 0.94 MAOB (0.44) KCNH2CYSLTR2CYSLTR1TRPA1TRPM2
SCHEMBL18052489 0.94 MAOB (0.44) KCNH2CYSLTR2CYSLTR1TRPA1TRPM2
SCHEMBL13108027 0.94 KCNH2 (0.50) KCNH2HTR2ACYSLTR2CYSLTR1TRPA1
SCHEMBL14227372 0.93 KCNH2 (0.49) KCNH2HTR2ACYSLTR2CYSLTR1TRPA1
SCHEMBL18417168 0.93 RELA (0.46) KCNH2CYSLTR2CYSLTR1TRPA1TRPM2
SCHEMBL18680229 0.93 MAOB (0.42) KCNH2CYSLTR2CYSLTR1TRPA1TRPM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9977354-B2 Coating liquid for electrophotographic photoreceptor production, electrophotographic photoreceptor, and image formation apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2018-05-22 US disclosed
US-20170090308-A1 COATING LIQUID FOR ELECTROPHOTOGRAPHIC PHOTORECEPTOR PRODUCTION, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMATION APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-30 US disclosed