Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18680403 | 0.86 | KDM4E (0.42) | HSD17B10MAPTKDM4ECASP1CASP7 | |
| SCHEMBL18662703 | 0.85 | CRHR1 (0.41) | HSD17B10CYP2C9ALOX15MAPTKDM4E | |
| SCHEMBL7546969 | 0.75 | POLB (0.49) | HSD17B10KDM4EPOLBALDH1A1TSHR | |
| SCHEMBL17285304 | 0.74 | KDM4E (0.41) | HSD17B10CYP2C9ALOX15KDM4ECASP1 | |
| Hydrochloric Acid SCHEMBL6993015 | 0.73 | POLB (0.47) | HSD17B10KDM4EPOLBALDH1A1TSHR | |
| SCHEMBL12949658 | 0.71 | CRHR1 (0.40) | HSD17B10CYP2C9ALOX15MAPTKDM4E | |
| SCHEMBL13555550 | 0.71 | POLB (0.45) | HSD17B10ALOX15MAPTKDM4ECASP1 | |
| Hydrochloric Acid SCHEMBL6992862 | 0.70 | POLB (0.47) | MAPTKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL11822627 | 0.65 | HSD17B10 (0.66) | HSD17B10CYP2C9ALOX15MAPTKDM4E | |
| SCHEMBL28326950 | 0.65 | MAPT (0.64) | HSD17B10CYP2C9ALOX15MAPTCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938240-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX INC. (CA) | 2018-04-10 | — | — | US | disclosed |
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | THE BANK OF NOVA SCOTIA (CA) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088518-A1 | Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones | FH, FECH, FPGS | HSD17B10 1265/4885CYP2C9 265/4885ALOX15 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.