SCHEMBL18680548

SCHEMBL18680548

c1ccc(-c2ccc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccnc6)c5c43)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ MDM2 Q00987 1/20 0.43
▸ ALOX12 P18054 1/20 0.42
▸ ALDH1A1 P00352 2/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ CYP1A2 P05177 3/20 0.39
▸ METAP2 P50579 3/20 0.39
▸ CYP11B2 P19099 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ G6PD P11413 1/20 0.38
▸ HSP90AA1 P07900 1/20 0.37
▸ PDE7A Q13946 1/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ IL1R1 P14778 1/20 0.37
▸ HDAC4 P56524 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19359918 0.93 L3MBTL1 (0.53) L3MBTL1KDM4EATMMDM2ALOX12
SCHEMBL15073805 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL17989838 0.90 L3MBTL1 (0.53) L3MBTL1KDM4EATMMDM2ALOX12
SCHEMBL10061605 0.87 CYP11B2 (0.46) L3MBTL1KDM4EATMMDM2ALOX12
SCHEMBL18593810 0.87 L3MBTL1 (0.61) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL17245347 0.87 L3MBTL1 (0.61) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL26329766 0.86 KDM4E (0.50) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL15074009 0.86 L3MBTL1 (0.41) L3MBTL1KDM4EATMMDM2ALDH1A1
SCHEMBL19359920 0.85 KMT2A (0.50) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL27426970 0.85 L3MBTL1 (0.59) L3MBTL1KDM4EATMALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210351362-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-11-11 — — US disclosed
US-11094891-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-08-17 — — US disclosed
US-20170271598-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-09-21 — — US disclosed
US-20170271598-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-09-21 — — US disclosed
US-20170092873-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-03-30 — — US disclosed
US-20170092873-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-03-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170092873-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OCIAD1 L3MBTL1 4804/4885KDM4E 3947/4885ATM 4217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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