Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.46 |
| ▸ | FABP7 | O15540 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10263692 | 0.91 | EPHX2 (0.43) | TSHRTDP1L3MBTL1KMT2AFABP5 | |
| SCHEMBL44676 | 0.86 | KMT2A (0.58) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL20903881 | 0.84 | KMT2A (0.51) | TSHRKMT2AFABP5FABP7EPHX2 | |
| SCHEMBL28180942 | 0.83 | KMT2A (0.50) | KMT2AFABP5FABP7EPHX2TP53 | |
| SCHEMBL10071038 | 0.81 | KMT2A (0.50) | L3MBTL1KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL23567985 | 0.80 | KMT2A (0.54) | KMT2AEPHX2 | |
| SCHEMBL13044481 | 0.80 | KMT2A (0.52) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL15119354 | 0.80 | KMT2A (0.60) | KMT2AFABP5FABP7EPHX2TP53 | |
| SCHEMBL14612149 | 0.79 | KMT2A (0.52) | KMT2AFABP5FABP7EPHX2CA1 | |
| SCHEMBL30954537 | 0.79 | TLR2 (0.49) | KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088706-A1 | COVALENT AND SUPRAMOLECULAR POLYMERS | UNITED STATES DEPARTMENT OF ENERGY | 2017-03-30 | — | — | US | disclosed |
| US-20170088706-A1 | COVALENT AND SUPRAMOLECULAR POLYMERS | UNITED STATES DEPARTMENT OF ENERGY | 2017-03-30 | — | — | US | disclosed |