Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28839000 | 0.84 | ALDH1A1 (0.53) | PDE10ACYSLTR1CYSLTR2GPBAR1TLR8 | |
| SCHEMBL19182788 | 0.80 | CYP1A2 (0.47) | PDE10ACYSLTR1CYSLTR2GPBAR1ALOX5AP | |
| SCHEMBL29873370 | 0.80 | ALDH1A1 (0.53) | PDE10AALDH1A1TP53TSHRACACB | |
| SCHEMBL113636 | 0.80 | ALDH1A1 (0.53) | PDE10AALDH1A1TP53TSHRACACB | |
| Quinoline SCHEMBL28287745 | 0.79 | KCNH2 (0.51) | PDE10ACYSLTR1CYSLTR2GPBAR1TLR8 | |
| SCHEMBL6115157 | 0.76 | ALDH1A1 (0.51) | PDE10AALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL29827516 | 0.76 | ALDH1A1 (0.51) | PDE10AALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL538491 | 0.76 | GPBAR1 (0.54) | PDE10ACYSLTR1CYSLTR2GPBAR1TLR8 | |
| SCHEMBL13034790 | 0.75 | ALDH1A1 (0.53) | PDE10AMAPK1ALDH1A1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL27600363 | 0.75 | GPBAR1 (0.52) | PDE10ACYSLTR1CYSLTR2GPBAR1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496682-A1 | DELIVERY PARTICLE | The Procter & Gamble Company (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011056935-A1 | DELIVERY PARTICLE | THE PROCTER & GAMBLE COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |