SCHEMBL538491

SCHEMBL538491

CCCCc1ccc2ccccc2n1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 3/20 0.54
CYSLTR1 Q9Y271 3/20 0.54
CYSLTR2 Q9NS75 2/20 0.54
TLR8 Q9NR97 2/20 0.51
PDE10A Q9Y233 4/20 0.51
KCNH2 Q12809 1/20 0.50
CYP1A2 P05177 3/20 0.47
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
TSHR P16473 1/20 0.45
NFKB1 P19838 1/20 0.45
MAPK1 P28482 1/20 0.45
CYP2C19 P33261 1/20 0.45
HIF1A Q16665 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27600363 0.98 GPBAR1 (0.52) GPBAR1CYSLTR1CYSLTR2TLR8PDE10A
Bromide SCHEMBL27600369 0.98 GPBAR1 (0.52) GPBAR1CYSLTR1CYSLTR2TLR8PDE10A
SCHEMBL10910525 0.96 GPBAR1 (0.51) GPBAR1CYSLTR1CYSLTR2TLR8PDE10A
SCHEMBL860157 0.94 KCNH2 (0.58) GPBAR1CYSLTR1CYSLTR2TLR8PDE10A
SCHEMBL797638 0.93 KCNH2 (0.61) GPBAR1CYSLTR1CYSLTR2TLR8PDE10A
SCHEMBL2514450 0.93 KCNH2 (0.61) GPBAR1CYSLTR1CYSLTR2TLR8PDE10A
SCHEMBL5367040 0.93 KCNH2 (0.61) GPBAR1CYSLTR1CYSLTR2TLR8PDE10A
SCHEMBL6114801 0.93 KCNH2 (0.61) GPBAR1CYSLTR1CYSLTR2TLR8PDE10A
SCHEMBL6114960 0.93 KCNH2 (0.61) GPBAR1CYSLTR1CYSLTR2TLR8PDE10A
SCHEMBL6115301 0.93 KCNH2 (0.61) GPBAR1CYSLTR1CYSLTR2TLR8PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 757 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH & CIE (CH) 2026-03-12 US claimed
US-20250163343-A1 FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT INTERNATIONAL FLAVORES & FRAGRANCES INC. 2025-05-22 US claimed
US-20250099349-A1 A FRAGRANCE MIXTURE SYMRISE AG (DE) 2025-03-27 US claimed
EP-4486857-A1 FRAGRANCE COMPOSITIONS FOR SLEEP IMPROVEMENT International Flavors & Fragrances Inc. (US) 2025-01-08 EP claimed
EP-4473079-A1 A FRAGRANCE MIXTURE Symrise AG (DE) 2024-12-11 EP claimed
CN-115210310-B Compositions and methods for waste polypropylene degradation 诺弗洛普有限公司 2024-08-30 CN claimed
CN-113873884-B Arthropod control composition 弗门尼舍有限公司 2024-06-14 CN claimed
US-20240173230-A1 FRAGRANCE COMPOSITION GIVAUDAN SA (CH) 2024-05-30 US claimed
EP-4319715-A1 FRAGRANCE COMPOSITION Givaudan SA (CH) 2024-02-14 EP claimed
US-11840610-B2 Compositions and methods for the degradation of waste polypropylene NOVOLOOP, INC. (US) 2023-12-12 US claimed
WO-2002098966-A2 AROMATIC PRINCIPLES FOR IMPROVING THE STABILITY IN STORAGE AND/OR FOR IMPROVING THE SOLUBILITY OF POLYVINYL ALCOHOLS AND/OR POLYVINYL ALCOHOLS WITH BONDED CELLULOSE DROM FRAGRANCES INTERNATIONAL KG (DE) 2002-12-12 WO claimed
CN-1094517-C Detergent composition containing efficient enduring perfume PROCTER & GAMBLE (US) 2002-11-20 CN claimed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
WO-2001085892-A1 HIGHLY CONCENTRATED FABRIC SOFTENER COMPOSITIONS AND ARTICLES CONTAINING SUCH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-11-15 WO claimed
WO-2001085888-A2 LAUNDRY SYSTEM HAVING UNITIZED DOSING THE PROCTER & GAMBLE COMPANY (US) 2001-11-15 WO claimed
CN-1169749-A Detergent compositions containing enduring perfume PROCTER & GAMBLE (US) 1998-01-07 CN claimed
EP-0805673-A1 PERSONAL TREATMENT COMPOSITIONS AND/OR COSMETIC COMPOSITIONS CONTAINING ENDURING PERFUME THE PROCTER & GAMBLE COMPANY (US) 1997-11-12 EP claimed
EP-0790820-A1 PERSONAL TREATMENT COMPOSITIONS AND/OR COSMETIC COMPOSITIONS CONTAINING ENDURING PERFUME THE PROCTER & GAMBLE COMPANY (US) 1997-08-27 EP claimed
WO-1996012467-A1 PERSONAL TREATMENT COMPOSITIONS AND/OR COSMETIC COMPOSITIONS CONTAINING ENDURING PERFUME THE PROCTER & GAMBLE COMPANY (US) 1996-05-02 WO claimed
WO-1996012468-A1 PERSONAL TREATMENT COMPOSITIONS AND/OR COSMETIC COMPOSITIONS CONTAINING ENDURING PERFUME THE PROCTER & GAMBLE COMPANY (US) 1996-05-02 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION CNOT9, MSL1, MT-CO2 GPBAR1 2701/4885CYSLTR1 1524/4885CYSLTR2 1727/4885
US-20250099349-A1 A FRAGRANCE MIXTURE PTMS, EP300, TRPA1 GPBAR1 3409/4885CYSLTR1 431/4885CYSLTR2 562/4885
US-20240173230-A1 FRAGRANCE COMPOSITION FABP2, FABP5, FAAH2 GPBAR1 633/4885CYSLTR1 206/4885CYSLTR2 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.