Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18683500 | 0.86 | LMNA (0.39) | LMNAPOLBCTSSCTSKMEN1 | |
| SCHEMBL18683131 | 0.85 | SYK (0.42) | LMNAPOLBCTSSCTSKMEN1 | |
| SCHEMBL21677218 | 0.85 | SYK (0.42) | LMNAPOLBCTSSCTSKMEN1 | |
| SCHEMBL21677169 | 0.81 | CTSS (0.39) | LMNAPOLBCTSSCTSKAAK1 | |
| SCHEMBL18683318 | 0.81 | CTSS (0.39) | LMNAPOLBCTSSCTSKAAK1 | |
| SCHEMBL18683358 | 0.81 | LMNA (0.38) | LMNAPOLBCTSSCTSKAAK1 | |
| SCHEMBL21677228 | 0.79 | LMNA (0.39) | LMNAPOLBCTSSCTSKMEN1 | |
| SCHEMBL17169212 | 0.79 | LMNA (0.39) | LMNAPOLBCTSSCTSKAAK1 | |
| SCHEMBL17169209 | 0.79 | LMNA (0.39) | LMNAPOLBCTSSCTSKAAK1 | |
| SCHEMBL18683370 | 0.79 | CTSS (0.40) | LMNAPOLBCTSSCTSKAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017050978-A1 | 2,3,4,5-TETRAHYDROPYRIDIN-6-AMINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-30 | — | — | WO | disclosed |