Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | CFB | P00751 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15590124 | 0.88 | CFB (0.38) | TRIM24TRIM33CFB | |
| SCHEMBL31136010 | 0.82 | CFB (0.45) | TRIM24TRIM33CFB | |
| SCHEMBL16400704 | 0.82 | CFB (0.45) | TRIM24TRIM33CFB | |
| SCHEMBL18683281 | 0.78 | P2RX7 (0.38) | TRIM24TRIM33CFB | |
| SCHEMBL15590525 | 0.72 | CFB (0.39) | CFB | |
| SCHEMBL15589671 | 0.71 | CFB (0.43) | TRIM24TRIM33CFB | |
| SCHEMBL15590153 | 0.71 | CFB (0.39) | TRIM24TRIM33CFB | |
| SCHEMBL15676169 | 0.71 | CYP2A6 (0.33) | — | |
| SCHEMBL15590276 | 0.70 | CFB (0.41) | TRIM24TRIM33CFB | |
| SCHEMBL24340277 | 0.69 | TRIM24 (0.43) | TRIM24TRIM33CFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855456-B1 | COMPLEMENT PATHWAY MODULATORS AND USES THEREOF | NOVARTIS AG (CH) | 2017-03-29 | — | — | EP | disclosed |