Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475662 | 0.93 | MDM2 (0.48) | MDM2PTPN1CTSL | |
| SCHEMBL12475679 | 0.93 | MDM2 (0.48) | MDM2PTPN1CTSL | |
| SCHEMBL12683247 | 0.89 | SSTR3 (0.47) | MDM2PTPN1CTSL | |
| SCHEMBL12476855 | 0.81 | MDM2 (0.38) | MDM2PTPN1CTSL | |
| SCHEMBL13402819 | 0.81 | MDM2 (0.59) | MDM2 | |
| SCHEMBL29470876 | 0.81 | MDM2 (0.59) | MDM2 | |
| SCHEMBL19402725 | 0.81 | MDM2 (0.59) | MDM2 | |
| SCHEMBL29414971 | 0.81 | MDM2 (0.59) | MDM2 | |
| SCHEMBL29379713 | 0.81 | MDM2 (0.59) | MDM2 | |
| SCHEMBL29649478 | 0.81 | SSTR3 (0.44) | PTPN1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147367-A1 | SMALL MOLECULE CONJUGATES FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2017-03-29 | — | — | EP | disclosed |