Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 6/20 | 0.59 |
| ▸ | MDM4 | O15151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29379713 | 1.00 | MDM2 (0.59) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL19402725 | 1.00 | MDM2 (0.59) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL13402819 | 1.00 | MDM2 (0.59) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL29414971 | 1.00 | MDM2 (0.59) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL29400571 | 0.93 | MDM2 (0.53) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL12527832 | 0.93 | MDM2 (0.53) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL31614333 | 0.93 | MDM2 (0.53) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL6158363 | 0.91 | MDM2 (0.57) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL436024 | 0.91 | MDM2 (0.57) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL31681399 | 0.91 | MDM2 (0.57) | MDM2MDM4TP53TLR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116472064-A | Antibody-drug conjugates and uses thereof | 昆山新蕴达生物科技有限公司 | 2023-07-21 | — | — | CN | claimed |
| WO-2022078279-A1 | ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 昆山新蕴达生物科技有限公司 | 2022-04-21 | — | — | WO | claimed |
| CN-116472064-A | Antibody-drug conjugates and uses thereof | 昆山新蕴达生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| WO-2022078279-A1 | ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 昆山新蕴达生物科技有限公司 | 2022-04-21 | — | — | WO | disclosed |