SCHEMBL29414971

SCHEMBL29414971

COc1ccc(C(NCCCCC(NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM2 Q00987 6/20 0.59
▸ MDM4 O15151 2/20 0.50
▸ TP53 P04637 2/20 0.50
▸ TLR2 O60603 2/20 0.45
▸ KMT2A Q03164 1/20 0.43
▸ CASP3 P42574 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379713 1.00 MDM2 (0.59) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29470876 1.00 MDM2 (0.59) MDM2MDM4TP53TLR2KMT2A
SCHEMBL19402725 1.00 MDM2 (0.59) MDM2MDM4TP53TLR2KMT2A
SCHEMBL13402819 1.00 MDM2 (0.59) MDM2MDM4TP53TLR2KMT2A
SCHEMBL29400571 0.93 MDM2 (0.53) MDM2MDM4TP53TLR2KMT2A
SCHEMBL12527832 0.93 MDM2 (0.53) MDM2MDM4TP53TLR2KMT2A
SCHEMBL31614333 0.93 MDM2 (0.53) MDM2MDM4TP53TLR2KMT2A
SCHEMBL6158363 0.91 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL436024 0.91 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A
SCHEMBL31681399 0.91 MDM2 (0.57) MDM2MDM4TP53TLR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986349-B Semex lattice preparation method of lupeptide 福建基诺厚普生物科技有限公司 2024-10-01 — — CN claimed
CN-117986349-A Preparation method of semaglutin 福建基诺厚普生物科技有限公司 2024-05-07 — — CN claimed
CN-117801052-A Method for synthesizing Fmoc-Lys (MMT) -OH 常州吉恩药业有限公司 2024-04-02 — — CN claimed
CN-115894633-A Preparation method of RGD cyclopeptide precursor 滨海吉尔多肽有限公司 2023-04-04 — — CN claimed
US-20250332184-A1 NEOADJUVANT USE OF ANTIBODY-DRUG CONJUGATES IMMUNOMEDICS INC (US) 2025-10-30 — — US disclosed
CN-120192374-A Targeted SctV cyclic peptide for inhibiting T3SS activity and application thereof 山东大学 2025-06-24 — — CN disclosed
EP-4569330-A1 NOVEL PORE MONOMERS AND PORES Oxford Nanopore Technologies PLC (GB) 2025-06-18 — — EP disclosed
CN-119654167-A Nucleic acid compositions comprising amphiphilic oligoethylene glycol (OEG) conjugated compounds and methods of using such compounds and compositions 生物技术公司 2025-03-18 — — CN disclosed
CN-119630970-A Novel Kong Shanti and holes 牛津纳米孔科技公开有限公司 2025-03-14 — — CN disclosed
WO-2025027389-A1 BIOLOGICALLY ACTIVE COMPOUNDS COMPRISING A STAPLED OR STITCHED PEPTIDE SUTURA THERAPEUTICS LIMITED (GB) 2025-02-06 — — WO disclosed
WO-2025027181-A1 AGENTS AND METHODS FOR TARGETED DELIVERY TO CELLS BioNTech SE (DE) 2025-02-06 — — WO disclosed
EP-4472998-A1 CYCLIC EPITOPE TAGS BioNTech SE (DE) 2024-12-11 — — EP disclosed
WO-2023023889-A1 METHOD OF SYNTHESIZING DENDRIMERIC AMPHIPHILE KAOHSIUNG MEDICAL UNIVERSITY (CN) 2023-03-02 — — WO disclosed
CN-115052632-A Targeted polypeptide-drug conjugates and uses thereof 北京海步医药科技有限公司 2022-09-13 — — CN disclosed
CN-115003679-A Conjugates of phthalocyanine dyes and antibodies or peptides 国立大学法人东京大学 2022-09-02 — — CN disclosed
CN-109562172-B Efficacy of anti-HLA-DR antibody drug conjugate IMMU-140(hL243-CL2A-SN-38) in HLA-DR positive cancers 免疫医疗公司 2022-08-16 — — CN disclosed
CN-110003055-B Amino diacids containing peptide modifiers 佩特雷化学和生物制药学实验室有限公司 2022-08-12 — — CN disclosed
CN-108853514-B Antibody drug conjugates with two different drugs 四川百利药业有限责任公司 2022-07-22 — — CN disclosed
CN-113444164-B Solid-phase synthesis method of Somalutide 台州吉诺生物科技有限公司 2022-07-19 — — CN disclosed
CN-110294800-B Preparation method of somaglutide 齐鲁制药有限公司 2022-03-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250332184-A1 NEOADJUVANT USE OF ANTIBODY-DRUG CONJUGATES ENTPD1, ENTPD2, ENTPD8 MDM2 1487/4885MDM4 1090/4885TP53 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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