SCHEMBL1868441

SCHEMBL1868441

COC(=O)c1ccc(C2=NC(c3ccccc3C#N)(n3c(-c4ccccc4C#N)nc(-c4ccc(C(=O)OC)cc4)c3-c3ccc(C(=O)OC)cc3)N=C2c2ccc(C(=O)OC)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 3/20 0.38
AKT2 P31751 3/20 0.38
ADORA2A P29274 2/20 0.37
IDO1 P14902 1/20 0.37
ALDH1A1 P00352 4/20 0.35
HPGD P15428 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.35
PKM P14618 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
MYC P01106 1/20 0.34
WDR5 P61964 1/20 0.34
KDM5A P29375 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1869117 0.91 AKT1 (0.41) AKT1AKT2ALDH1A1HPGDSMN1; SMN2
SCHEMBL2793729 0.90 TNK2 (0.37) AKT1AKT2ALDH1A1HPGDSMN1; SMN2
SCHEMBL1864620 0.85 TNK2 (0.37) AKT1AKT2ADORA2AALDH1A1HPGD
SCHEMBL1865943 0.84 AKT1 (0.41) AKT1AKT2IDO1ALDH1A1HPGD
SCHEMBL1867410 0.84 AKT1 (0.44) AKT1AKT2IDO1ALDH1A1HPGD
SCHEMBL1868528 0.83 MAPT (0.40) AKT1AKT2IDO1ALDH1A1HPGD
SCHEMBL1864872 0.83 AKT1 (0.40) AKT1AKT2IDO1ALDH1A1HPGD
SCHEMBL1867498 0.82 AKT1 (0.39) AKT1AKT2IDO1ALDH1A1HPGD
SCHEMBL1871895 0.76 AKT1 (0.43) AKT1AKT2ALDH1A1SMN1; SMN2KDM4E
SCHEMBL1867483 0.76 AKT1 (0.47) AKT1AKT2ALDH1A1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935776-B2 having a carboxy group in its main chain and a acryloyl group in its side chain; Color filters AGI CORPORATION (TW) 2011-05-03 US disclosed
US-20080234403-A1 Radiation curable and developable polyurethane and radiation curable and developable photo resist composition containing the same AGI CORPORATION (TW) 2008-09-25 US disclosed
US-6627364-B2 Contains (A) a colorant, (B) a binder resin and (C) a solvent having a boiling point of 245 degrees C. or more at normal pressure. SEIKO EPSON CORPORATION (JP) 2003-09-30 US disclosed
US-20020128351-A1 Ink jet color filter resin composition, color filter and color filter production process SEIKO EPSON CORPORATION (JP) 2002-09-12 US disclosed
US-6368774-B1 MIXTURE CONTAINING ISOINDOLININE DYE JSR CORPORATION (JP) 2002-04-09 US disclosed
US-6348298-B1 COMPOSITION CONSISTING OF COLORANT CONTAINING PHTHALOCYANINE BLUE AND PHTHALOCYANINE GREEN OR PIGMENT GREEN 36, ALKALI-SOLUBLE RESIN, POLYFUNCTIONAL MONOMER, AND PHOTOPOLYMERIZATION INITIATOR JSR CORPORATION (JP) 2002-02-19 US disclosed
US-6140019-A Radiation sensitive composition JSR CORPORATION (JP) 2000-10-31 US disclosed
EP-1033625-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 EP disclosed
EP-1033626-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 EP disclosed
US-6013415-A Radiation sensitive composition JSR CORPORATION (JP) 2000-01-11 US disclosed
EP-0893737-A2 Radiation sensitive composition JSR Corporation (JP) 1999-01-27 EP disclosed