SCHEMBL1864620

SCHEMBL1864620

N#Cc1ccccc1-c1nc(-c2ccccc2)c(-c2ccccc2)n1C1(c2ccccc2C#N)N=C(c2ccccc2)C(c2ccccc2)=N1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 1/20 0.37
ALDH1A1 P00352 3/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
AKT1 P31749 1/20 0.35
AKT2 P31751 1/20 0.35
KDM4E B2RXH2 1/20 0.34
HTT P42858 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
GABRG2 P18507 5/20 0.33
GABRB3 P28472 5/20 0.33
GABRA5 P31644 4/20 0.33
GABRA3 P34903 4/20 0.33
GABRA1 P14867 4/20 0.33
GABRA2 P47869 3/20 0.33
HPGD P15428 1/20 0.33
CHEK1 O14757 1/20 0.33
ABL1 P00519 1/20 0.33
PDGFRB P09619 1/20 0.33
PDGFRA P16234 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2793729 0.85 TNK2 (0.37) TNK2ALDH1A1AKT1AKT2KDM4E
SCHEMBL1868441 0.85 AKT1 (0.38) ALDH1A1LMNAAKT1AKT2KDM4E
SCHEMBL17133349 0.84 BCHE (0.36) ALDH1A1LMNAAKT1AKT2KDM4E
SCHEMBL1870282 0.84 AKT1 (0.38) ALDH1A1LMNATHRBAKT1AKT2
SCHEMBL1869117 0.83 AKT1 (0.41) ALDH1A1LMNAAKT1AKT2KDM4E
SCHEMBL1865434 0.82 FABP4 (0.35) ALDH1A1LMNAAKT1AKT2KDM4E
SCHEMBL30343795 0.79 AKT1 (0.36) ALDH1A1LMNAAKT1AKT2KDM4E
SCHEMBL309105 0.79 AKT1 (0.36) ALDH1A1LMNAAKT1AKT2KDM4E
SCHEMBL4452418 0.78 AKT1 (0.35) ALDH1A1AKT1AKT2ADORA2AADORA1
SCHEMBL307900 0.78 MAPK1 (0.34) ALDH1A1AKT1AKT2KDM4EBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935776-B2 having a carboxy group in its main chain and a acryloyl group in its side chain; Color filters AGI CORPORATION (TW) 2011-05-03 US disclosed
US-20080234403-A1 Radiation curable and developable polyurethane and radiation curable and developable photo resist composition containing the same AGI CORPORATION (TW) 2008-09-25 US disclosed
US-6368774-B1 MIXTURE CONTAINING ISOINDOLININE DYE JSR CORPORATION (JP) 2002-04-09 US disclosed
US-6348298-B1 COMPOSITION CONSISTING OF COLORANT CONTAINING PHTHALOCYANINE BLUE AND PHTHALOCYANINE GREEN OR PIGMENT GREEN 36, ALKALI-SOLUBLE RESIN, POLYFUNCTIONAL MONOMER, AND PHOTOPOLYMERIZATION INITIATOR JSR CORPORATION (JP) 2002-02-19 US disclosed
US-6140019-A Radiation sensitive composition JSR CORPORATION (JP) 2000-10-31 US disclosed
EP-1033626-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 EP disclosed
EP-1033625-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 EP disclosed
US-6013415-A Radiation sensitive composition JSR CORPORATION (JP) 2000-01-11 US disclosed
EP-0893737-A2 Radiation sensitive composition JSR Corporation (JP) 1999-01-27 EP disclosed